CEACAM5

CEACAM5 (Carcinoembryonic Antigen Cell Adhesion Molecule 5), also known as CEA (Carcinoembryonic Antigen), is a membrane glycoprotein mainly expressed in the intestine, pancreas, bile ducts, and liver. Its functions include cell adhesion, cell signaling, and immune regulation. CEACAM5 is also highly expressed in many malignant tumor cells, making it a widely used biomarker for cancer diagnosis and monitoring. Although the role of CEACAM5 in cancer treatment requires further investigation, it has been widely applied in the diagnosis and treatment of various cancers as a tumor marker.

Popular Product

Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 5(CEACAM5)(E398K),partial (Active) (CSB-MP005165HU)

Validated Data

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM5 at 2μg/mL can bind Anti-CEACAM5 recombinant antibody (CSB-RA005165MA1HU), the EC₅₀ is 0.8955-1.719 ng/mL.