The gene FGF4 encodes the protein Fibroblast Growth Factor 4 (FGF4), also known as HST-1 or HBGF-4. FGF4 is a mitogenic protein that plays critical roles in embryonic development and cell growth. It interacts with FGF receptors (FGFRs) to activate signaling pathways, including the RAS/MAP kinase, PI3/AKT, and PLCγ pathways. Dysregulation of FGF4 is associated with various diseases, such as cancer, where it is often overexpressed. Research into FGF4 has led to the development of potential therapeutic strategies, including FGFR inhibitors for cancer treatment.
Recombinant Human Fibroblast growth factor 4 (FGF4) (Active) (CSB-MP008631HU-WD)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Validated Data
Western Blot analysis of NIH-3T3 Hela cells using FGF-4 Polyclonal Antibody
The following FGF4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FGF4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA006114 | FGF4 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA910266 | FGF4 Antibody | Human,Mouse | ELISA,IHC |
CSB-PA008631OA01HU | FGF4 Antibody | Human | ELISA, IHC |
CSB-PA008631OB01HU | FGF4 Antibody, HRP conjugated | Human | ELISA |
CSB-PA008631OC01HU | FGF4 Antibody, FITC conjugated | Human | |
CSB-PA008631OD01HU | FGF4 Antibody, Biotin conjugated | Human | ELISA |
FGF4 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP008631MO CSB-EP008631MO CSB-BP008631MO CSB-MP008631MO CSB-EP008631MO-B |
Recombinant Mouse Fibroblast growth factor 4 (Fgf4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF4 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP008631BO CSB-EP008631BO CSB-BP008631BO CSB-MP008631BO CSB-EP008631BO-B |
Recombinant Bovine Fibroblast growth factor 4 (FGF4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF4 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP008631CH CSB-EP008631CH CSB-BP008631CH CSB-MP008631CH CSB-EP008631CH-B |
Recombinant Chicken Fibroblast growth factor 4 (FGF4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP008631HU CSB-EP008631HU CSB-BP008631HU CSB-MP008631HU CSB-EP008631HU-B |
Recombinant Human Fibroblast growth factor 4 (FGF4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP002411HU | Recombinant Human Fibroblast growth factor 4 protein (FGF4), partial (Active) | E.coli |
CSB-AP003981HU | Recombinant Human Fibroblast growth factor 4 (FGF4), partial (Active) | E.coli |
CSB-MP008631HU-WD | Recombinant Human Fibroblast growth factor 4 (FGF4) (Active) | Mammalian cell |
FGF4 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04548h | Human fibroblast growth factor 4 (FGF4) ELISA kit | serum, plasma, tissue homogenates | 1.56 pg/mL |