GPX1

Glutathione peroxidase 1 (GPX1), a key member of the glutathione peroxidase family, is often referred to as cellular glutathione peroxidase. It uses glutathione as a cofactor to catalyze the reduction of hydrogen peroxide and lipid hydroperoxides, thereby reducing oxidative damage to cells. It also interacts with the Nrf2-ARE pathway to maintain cellular redox balance.
Abnormal GPX1 expression or activity is linked to diseases like diabetes, cardiovascular disorders, and certain cancers. Current research focuses on developing GPX1 mimetics (e.g., ebselen) to enhance antioxidant capacity. Additionally, gene therapy approaches to restore GPX1 function in deficient tissues show promising preclinical results for treating oxidative stress-related diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GPX1 Antibody (CSB-PA009866KA01HU)

Validated Data

Western blot analysis of extracts of various cell lines, using GPX1 antibody.

Human Glutathione peroxidase 1(GPX1) ELISA kit (CSB-EL009866HU)

Validated Data

Code: CSB-EL009866HU

Size: 96T,5×96T,10×96T

Sensitivity: 3.9 μU/mL

Detection Range: 15.6 μU/mL-1000 μU/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following GPX1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

GPX1 Antibodies

GPX1 Proteins

GPX1 ELISA Kits

GPX1 Antibodies

GPX1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA009866KA01HU	GPX1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-RA009866A0HU	GPX1 Recombinant Monoclonal Antibody	Human	ELISA
CSB-PA009866ZA01HU	GPX1 Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)
CSB-PA009866ZA01HU	GPX1 Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)

GPX1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA346343XA01DOA	GPX1 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

GPX1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA009866XA01SVG	GPX1 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

GPX1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA528886XA01SXV	gpx1 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

GPX1 Proteins

GPX1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP009866MO CSB-EP009866MO CSB-BP009866MO CSB-MP009866MO CSB-EP009866MO-B	Recombinant Mouse Glutathione peroxidase 1 (Gpx1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP009866RB CSB-EP009866RB CSB-BP009866RB CSB-MP009866RB CSB-EP009866RB-B	Recombinant Rabbit Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP009866HU CSB-BP009866HU CSB-MP009866HU CSB-EP009866HU-B	Recombinant Human Glutathione peroxidase 1 (GPX1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP009866HU	Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S)	E.coli
CSB-EP009866HUa2	Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S)	E.coli

GPX1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP009866BO CSB-EP009866BO CSB-BP009866BO CSB-MP009866BO CSB-EP009866BO-B	Recombinant Bovine Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Source
CSB-YP009866SVG CSB-EP009866SVG CSB-BP009866SVG CSB-MP009866SVG CSB-EP009866SVG-B	Recombinant Saccharomyces cerevisiae Glutathione peroxidase-like peroxiredoxin 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP009866RA CSB-EP009866RA CSB-BP009866RA CSB-MP009866RA CSB-EP009866RA-B	Recombinant Rat Glutathione peroxidase 1 (Gpx1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Synechocystis sp. (strain PCC 6803 / Kazusa)

Code	Product Name	Source
CSB-YP300400SSQ CSB-EP300400SSQ CSB-BP300400SSQ CSB-MP300400SSQ CSB-EP300400SSQ-B	Recombinant Synechocystis sp. Putative glutathione peroxidase (slr1171)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Schistosoma mansoni (Blood fluke)

Code	Product Name	Source
CSB-YP308789SXQ CSB-EP308789SXQ CSB-BP308789SXQ CSB-MP308789SXQ CSB-EP308789SXQ-B	Recombinant Schistosoma mansoni Glutathione peroxidase (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP346343DOA CSB-EP346343DOA CSB-BP346343DOA CSB-MP346343DOA CSB-EP346343DOA-B	Recombinant Arabidopsis thaliana Phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP528886SXV CSB-EP528886SXV CSB-BP528886SXV CSB-MP528886SXV CSB-EP528886SXV-B	Recombinant Schizosaccharomyces pombe Glutathione peroxidase (gpx1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Macaca fuscata fuscata (Japanese macaque)

Code	Product Name	Source
CSB-YP009866MMX CSB-EP009866MMX CSB-BP009866MMX CSB-MP009866MMX CSB-EP009866MMX-B	Recombinant Macaca fuscata fuscata Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP009866PI CSB-EP009866PI CSB-BP009866PI CSB-MP009866PI CSB-EP009866PI-B	Recombinant Pig Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP009866EQV CSB-EP009866EQV CSB-BP009866EQV CSB-MP009866EQV CSB-EP009866EQV-B	Recombinant Pan troglodytes Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

Code	Product Name	Source
CSB-YP009866CYL CSB-EP009866CYL CSB-BP009866CYL CSB-MP009866CYL CSB-EP009866CYL-B	Recombinant Callithrix jacchus Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Hylobates lar (Common gibbon) (White-handed gibbon)

Code	Product Name	Source
CSB-YP009866HXW CSB-EP009866HXW CSB-BP009866HXW CSB-MP009866HXW CSB-EP009866HXW-B	Recombinant Hylobates lar Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Sapajus apella (Brown-capped capuchin) (Cebus apella)

Code	Product Name	Source
CSB-YP009866DQU CSB-EP009866DQU CSB-BP009866DQU CSB-MP009866DQU CSB-EP009866DQU-B	Recombinant Cebus apella Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Pongo pygmaeus (Bornean orangutan)

Code	Product Name	Source
CSB-YP009866EXP CSB-EP009866EXP CSB-BP009866EXP CSB-MP009866EXP CSB-EP009866EXP-B	Recombinant Pongo pygmaeus Glutathione peroxidase 1 (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPX1 Proteins for Molluscum contagiosum virus subtype 1 (MOCV) (MCVI)

Code	Product Name	Source
CSB-YP836519MHI CSB-EP836519MHI CSB-BP836519MHI CSB-MP836519MHI CSB-EP836519MHI-B	Recombinant Molluscum contagiosum virus subtype 1 Glutathione peroxidase (GPX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli