MELTF

The MELTF gene encodes a protein called Meiosis - specific with coiled - coil domain and FHA domain - containing protein. There are currently no well - known common aliases. The protein is mainly involved in meiosis, contributing to the normal pairing and recombination of homologous chromosomes. It interacts with other proteins in the meiotic process, ensuring the accurate segregation of chromosomes.
MELTF is associated with the meiosis - related signal pathway. Disruptions in MELTF can lead to meiotic defects, which may cause infertility in both males and females. As of now, there is limited progress in drug development specifically targeting MELTF. However, further research in this area could potentially open new avenues for treating related reproductive diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human MELTF at 2 μg/ml can bind Anti-MELTF recombinant antibody (CSB-RA013754MA1HU). The EC₅₀ is 0.3476-0.4529 ng/mL.

Recombinant Human Melanotransferrin (MELTF) (CSB-EP013754HU)

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MELTF Antibody (CSB-PA013754LA01HU)

Validated Data

Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate
All lanes: MELTF antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 81, 33 kDa
Observed band size: 81 kDa

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA013754LA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA013754LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Melanotransferrin(MFI2) ELISA kit (CSB-EL013754HU)

Validated Data

Code: CSB-EL013754HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.039 ng/mL

Detection Range: 0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following MELTF reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

MELTF Antibodies

MELTF Proteins

MELTF ELISA Kits

MELTF Antibodies

MELTF Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA013754GA01HU	MFI2 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA013754LA01HU	MELTF Antibody	Human	ELISA, WB, IHC, IF

MELTF Antibodies for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Species Reactivity	Application
CSB-PA013754ZA01RB	MELTF Antibody	Oryctolagus cuniculus	ELISA, WB (ensure identification of antigen)

MELTF Proteins

MELTF Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-BP013754HU CSB-MP013754HU CSB-EP013754HU-B	Recombinant Human Melanotransferrin (MFI2)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP013754HU	Recombinant Human Melanotransferrin (MELTF)	E.coli
CSB-YP013754HU	Recombinant Human Melanotransferrin (MFI2)	Yeast
CSB-MP013754HU1	Recombinant Human Melanotransferrin (MELTF) (Active)	Mammalian cell

MELTF Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP013754RB CSB-BP013754RB CSB-MP013754RB CSB-EP013754RB-B	Recombinant Rabbit Melanotransferrin (Mfi2), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP013754RB	Recombinant Rabbit Melanotransferrin (Mfi2), partial	E.coli

MELTF Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP882604MO CSB-EP882604MO CSB-BP882604MO CSB-MP882604MO CSB-EP882604MO-B	Recombinant Mouse Melanotransferrin (Mfi2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MELTF ELISA Kit

MELTF ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL013754HU	Human Melanotransferrin(MFI2) ELISA kit	serum, plasma, tissue homogenates, cell lysates	0.039 ng/mL

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MELTF

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