APLNR, known as Apelin Receptor, is also commonly referred to as APJ. This protein belongs to the G - protein - coupled receptor family. It plays a crucial role in regulating cardiovascular function, fluid homeostasis, and energy metabolism. It signals through multiple pathways such as the Gi/o pathway, influencing cell growth, migration, and angiogenesis.
Dysregulation of APLNR is associated with various diseases, including heart failure, hypertension, and obesity. In drug development, targeting APLNR has shown potential. Several peptide and non - peptide agonists and antagonists have been investigated, aiming to modulate its activity for therapeutic benefits in related diseases.
APLNR Antibody (CSB-PA001910EA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA001910EA01HU at dilution of 1:100
Immunofluorescent analysis of A431 cells using CSB-PA001910EA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Human Apelin receptor(APLNR) ELISA kit (CSB-EL001910HU)
Validated Data
Code: CSB-EL001910HU
Size: 96T,5×96T,10×96T
Sensitivity: 5.8 pg/mL
Detection Range: 23.5 pg/mL-1500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following APLNR reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
APLNR Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA007868 | APLNR Antibody | Human | WB, IHC, IF, ELISA |
CSB-PA963250 | APLNR Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA229044 | APLNR Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA165028 | APLNR Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA001910EA01HU | APLNR Antibody | Human | ELISA, IHC, IF |
APLNR Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA001910ZA01MO | Aplnr Antibody | Mus musculus | ELISA, WB (ensure identification of antigen) |
APLNR Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Code | Product Name | Source |
---|---|---|
CSB-CF001910XBF | Recombinant Xenopus tropicalis Apelin receptor (aplnr) | in vitro E.coli expression system |
CSB-YP001910XBF1 CSB-EP001910XBF1 CSB-BP001910XBF1 CSB-MP001910XBF1 CSB-EP001910XBF1-B |
Recombinant Xenopus tropicalis Apelin receptor (aplnr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APLNR Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF001910RA | Recombinant Rat Apelin receptor (Aplnr) | in vitro E.coli expression system |
CSB-YP001910RA1 CSB-EP001910RA1 CSB-BP001910RA1 CSB-MP001910RA1 CSB-EP001910RA1-B |
Recombinant Rat Apelin receptor (Aplnr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APLNR Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF001910MO | Recombinant Mouse Apelin receptor (Aplnr) | in vitro E.coli expression system |
CSB-YP001910MO1 CSB-BP001910MO1 CSB-MP001910MO1 CSB-EP001910MO1-B |
Recombinant Mouse Apelin receptor (Aplnr), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP001910MO1 | Recombinant Mouse Apelin receptor (Aplnr), partial | E.coli |
APLNR Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF001910HU | Recombinant Human Apelin receptor (APLNR) | in vitro E.coli expression system |
CSB-YP001910HU1 CSB-EP001910HU1 CSB-BP001910HU1 CSB-MP001910HU1 CSB-EP001910HU1-B |
Recombinant Human Apelin receptor (APLNR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APLNR Proteins for Macaca mulatta (Rhesus macaque)
Code | Product Name | Source |
---|---|---|
CSB-CF001910MOW | Recombinant Macaca mulatta Apelin receptor (APLNR) | in vitro E.coli expression system |
CSB-YP001910MOW1 CSB-EP001910MOW1 CSB-BP001910MOW1 CSB-MP001910MOW1 CSB-EP001910MOW1-B |
Recombinant Macaca mulatta Apelin receptor (APLNR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APLNR ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL001910HU | Human Apelin receptor(APLNR) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 5.8 pg/mL |