The protein encoded by the CHRNA1 gene is a component of the neuronal nicotinic acetylcholine receptor known as the α1 subtype. Its structure includes transmembrane domains and ligand-binding domains. This protein forms ion channels at the neuromuscular junction, mediating signal transmission between nerve impulses and muscle contractions by regulating the binding of acetylcholine. Functionally, CHRNA1 is involved in modulating nerve impulse transmission necessary for muscle contractions. Its role at the neuromuscular junction is essential in triggering muscle contractions in response to nerve impulses, crucial for muscle movement. The CHRNA1 gene and its encoded protein are implicated in the pathogenesis of various neuromuscular diseases. Mutations or abnormalities may lead to certain neuromuscular disorders such as Congenital Myasthenic Syndromes (CMS). Research on the CHRNA1 gene contributes to understanding the mechanisms behind these diseases and aids in the development of therapeutic interventions.
Recombinant Human Acetylcholine receptor subunit alpha (CHRNA1), partial
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP005386HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CHRNA1.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP005386HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CHRNA1.
The following CHRNA1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CHRNA1 Antibodies for Torpedo californica
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA005386LA01TOT | CHRNA1 Antibody |
Torpedo californica | ELISA, WB |
CHRNA1 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA005386LA01MO | Chrna1 Antibody |
Mouse, Human | ELISA, WB |
CSB-PA005386LB01MO | Chrna1 Antibody, HRP conjugated |
Mouse | ELISA |
CHRNA1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA11789A0Rb | CHRNA1 Antibody |
Human, Rat | ELISA, WB, IHC |
CSB-PA11789D0Rb | CHRNA1 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA006117 | CHRNA1 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA006818 | CHRNA1 Antibody |
Human,Mouse,Rat | IHC, ELISA |
CSB-PA169699 | CHRNA1 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA587496 | CHRNA1 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CHRNA1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP005386HU | Recombinant Human Acetylcholine receptor subunit alpha (CHRNA1), partial |
E.coli |
CSB-MP005386HU |
Recombinant Human Acetylcholine receptor subunit alpha (CHRNA1), partial |
Mammalian cell |
CSB-EP005386HUc2 | Recombinant Human Acetylcholine receptor subunit alpha (CHRNA1), partial |
E.coli |
CSB-YP005386HUe9 | Recombinant Human Acetylcholine receptor subunit alpha (CHRNA1), partial |
Yeast |
CSB-BP005386HU | Recombinant Human Acetylcholine receptor subunit alpha (CHRNA1), partial |
Baculovirus |
CSB-EP005386HU-B | Recombinant Human Acetylcholine receptor subunit alpha (CHRNA1), partial, Biotinylated |
E.coli |
CHRNA1 Proteins for Torpedo californica (Pacific electric ray)
Code | Product Name | Source |
---|---|---|
CSB-EP005386TOT | Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial |
E.coli |
CSB-EP005386TOT-B |
Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial |
In Vivo Biotinylation in E.coli |
CSB-EP005386TOTe1 | Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial |
E.coli |
CSB-EP005386TOTb1 | Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial |
E.coli |
CHRNA1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP005386MO | Recombinant Mouse Acetylcholine receptor subunit alpha (Chrna1), partial,Yeast |
Yeast |
CSB-EP005386MO | Recombinant Mouse Acetylcholine receptor subunit alpha (Chrna1), partial |
E.coli |
CSB-BP005386MO CSB-MP005386MO CSB-EP005386MO-B |
Recombinant mouse Acetylcholine receptor subunit alpha (Chrna1), partial |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP005386MOa2 | Recombinant Mouse Acetylcholine receptor subunit alpha (Chrna1), partial |
E.coli |
CHRNA1 Proteins for Tetronarce californica (Pacific electric ray) (Torpedo californica)
Code | Product Name | Source |
---|---|---|
CSB-EP005386TOTa2 | Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial |
E.coli |
CSB-YP005386TOT | Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial |
Yeast |
CSB-BP005386TOT | Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial |
Baculovirus |
CSB-MP005386TOT | Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial |
Mammalian cell |