TNF

Tumor necrosis factor is a protein in humans that is encoded by TNF gene. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective

The following TNF reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TNF Antibodies

TNF Proteins

TNF ELISA Kits

TNF Antibodies

TNF Antibodies for Ovis aries (Sheep)

Code	Product Name	Species Reactivity	Application
CSB-PA023955DC01SH	TNF Antibody, FITC conjugated	Sheep
CSB-PA023955DB01SH	TNF Antibody, HRP conjugated	Sheep	ELISA
CSB-PA023955DA01SH	TNF Antibody	Sheep	ELISA, WB
CSB-PA023955DD01SH	TNF Antibody, Biotin conjugated	Sheep	ELISA

TNF Antibodies for Bos taurus (Bovine)

Code	Product Name	Species Reactivity	Application
CSB-PA08474A0Rb	TNF Antibody	Bovine	ELISA, WB
CSB-PA08474C0Rb	TNF Antibody, FITC conjugated	Bovine

TNF Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA07427D0Rb	TNF Antibody, Biotin conjugated	Human	ELISA
CSB-PA07427C0Rb	TNF Antibody, FITC conjugated	Human
CSB-PA07427B0Rb	TNF Antibody, HRP conjugated	Human	ELISA
CSB-PA07427A0Rb	TNF Antibody	Human	ELISA, WB, IHC, IF
CSB-PA023955KA01HU	TNF Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA147864	TNF Antibody	Human,Mouse	ELISA,IHC,IF
CSB-PA004310	TNF Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA004963	TNF Antibody	Human	WB, ELISA
CSB-PA080266	TNF Antibody	Human,Mouse,Rat	WB
CSB-PA080267	TNF Antibody	Human,Mouse,Rat	WB, IHC
CSB-MA080271	TNF Monoclonal Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-MA080272	TNF Monoclonal Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA954619	TNF Antibody	Human	ELISA,IHC

TNF Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA023955XA01MO	Tnf Antibody	Mus musculus (Mouse)	ELISA, WB (ensure identification of antigen)
CSB-PA023955ZA01MO	Tnf Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

TNF Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA325438XA01RA	Tnf Antibody	Rattus norvegicus (Rat)	ELISA, WB (ensure identification of antigen)

TNF Antibodies for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Species Reactivity	Application
CSB-PA023955XA01RB	TNF Antibody	Oryctolagus cuniculus (Rabbit)	ELISA, WB (ensure identification of antigen)

TNF Antibodies for Marmota monax

Code	Product Name	Species Reactivity	Application
CSB-PA523593ZA01MQG	TNF Antibody	Marmota monax	ELISA, WB

TNF Proteins

TNF Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP023955BO CSB-BP023955BO CSB-MP023955BO CSB-EP023955BO-B	Recombinant Bovine Tumor necrosis factor(TNF),partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023955BO(A4)	Recombinant Bovine Tumor necrosis factor(TNF)	in vitro E.coli expression system
CSB-EP023955BOe0	Recombinant Bovie Tumor necrosis factor(TNF),partial	E.coli
CSB-EP023955BO	Recombinant Bovie Tumor necrosis factor(TNF),partial	E.coli

TNF Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP023955SH	Recombinant Sheep Tumor necrosis factor(TNF),partial,partial	Yeast
CSB-EP023955SH	Recombinant Sheep Tumor necrosis factor(TNF),partial	E.coli
CSB-BP023955SH CSB-MP023955SH CSB-EP023955SH-B	Recombinant Sheep Tumor necrosis factor(TNF),partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Cavia porcellus (Guinea pig)

Code	Product Name	Source
CSB-YP023955GU CSB-EP023955GU CSB-BP023955GU CSB-MP023955GU CSB-EP023955GU-B	Recombinant Guinea pig Tumor necrosis factor(TNF)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP023955DO CSB-EP023955DO CSB-BP023955DO CSB-MP023955DO CSB-EP023955DO-B	Recombinant Dog Tumor necrosis factor(TNF)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP023955MO1 CSB-BP023955MO1 CSB-MP023955MO1 CSB-EP023955MO1-B	Recombinant Mouse Tumor necrosis factor(Tnf), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003471MO	Recombinant Mouse Tumor necrosis factor protein(Tnf),partial (Active)	E.coli
CSB-EP023955MO1	Recombinant Mouse Tumor necrosis factor(Tnf),partial	E.coli
CSB-CF023955MO	Recombinant Mouse Tumor necrosis factor(Tnf)	in vitro E.coli expression system
CSB-YP023955MO1 CSB-EP023955MO1 CSB-BP023955MO1 CSB-MP023955MO1 CSB-EP023955MO1-B	Recombinant Mouse Tumor necrosis factor(Tnf),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP005031MO	Recombinant Mouse Tumor necrosis factor(Tnf),partial (Active)	E.coli

TNF Proteins for Trichosurus vulpecula (Brush-tailed possum)

Code	Product Name	Source
CSB-YP302104TQG CSB-EP302104TQG CSB-BP302104TQG CSB-MP302104TQG CSB-EP302104TQG-B	Recombinant Trichosurus vulpecula Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP304440MOV CSB-EP304440MOV CSB-BP304440MOV CSB-MP304440MOV CSB-EP304440MOV-B	Recombinant Macaca fascicularis Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP325438RA CSB-EP325438RA CSB-BP325438RA CSB-MP325438RA CSB-EP325438RA-B	Recombinant Rat Tumor necrosis factor(Tnf),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Papio sp. (Baboon)

Code	Product Name	Source
CSB-YP335848PBS CSB-EP335848PBS CSB-BP335848PBS CSB-MP335848PBS CSB-EP335848PBS-B	Recombinant Papio sp. Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Peromyscus leucopus (White-footed mouse)

Code	Product Name	Source
CSB-YP339754ETX CSB-EP339754ETX CSB-BP339754ETX CSB-MP339754ETX CSB-EP339754ETX-B	Recombinant Peromyscus leucopus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Cervus elaphus (Red deer)

Code	Product Name	Source
CSB-YP343176DRN CSB-EP343176DRN CSB-BP343176DRN CSB-MP343176DRN CSB-EP343176DRN-B	Recombinant Cervus elaphus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Bos indicus (Zebu)

Code	Product Name	Source
CSB-YP348690BUL CSB-EP348690BUL CSB-BP348690BUL CSB-MP348690BUL CSB-EP348690BUL-B	Recombinant Bos indicus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Bubalus bubalis (Domestic water buffalo)

Code	Product Name	Source
CSB-YP352606BWX CSB-EP352606BWX CSB-BP352606BWX CSB-MP352606BWX CSB-EP352606BWX-B	Recombinant Bubalus bubalis Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Lama glama (Llama)

Code	Product Name	Source
CSB-YP352952LBS CSB-EP352952LBS CSB-BP352952LBS CSB-MP352952LBS CSB-EP352952LBS-B	Recombinant Lama glama Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Papio anubis (Olive baboon)

Code	Product Name	Source
CSB-YP352968ERI CSB-EP352968ERI CSB-BP352968ERI CSB-MP352968ERI CSB-EP352968ERI-B	Recombinant Papio anubis Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Marmota monax (Woodchuck)

Code	Product Name	Source
CSB-YP523593MQG	Recombinant Marmota monax Tumor necrosis factor(TNF),partial,Yeast	Yeast
CSB-EP523593MQG	Recombinant Marmota monax Tumor necrosis factor(TNF),partial	E.coli
CSB-BP523593MQG	Recombinant Marmota monax Tumor necrosis factor(TNF),partial	Baculovirus
CSB-MP523593MQG CSB-EP523593MQG-B	Recombinant Marmota monax Tumor necrosis factor(TNF),partial	Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Papio hamadryas ursinus (Chacma baboon)

Code	Product Name	Source
CSB-YP525660ERK CSB-EP525660ERK CSB-BP525660ERK CSB-MP525660ERK CSB-EP525660ERK-B	Recombinant Papio hamadryas ursinus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Macropus eugenii (Tammar wallaby) (Notamacropus eugenii)

Code	Product Name	Source
CSB-YP528008MPE CSB-EP528008MPE CSB-BP528008MPE CSB-MP528008MPE CSB-EP528008MPE-B	Recombinant Macropus eugenii Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Callithrix jacchus (White-tufted-ear marmoset)

Code	Product Name	Source
CSB-YP622179CYL CSB-EP622179CYL CSB-BP622179CYL CSB-MP622179CYL CSB-EP622179CYL-B	Recombinant Callithrix jacchus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Boselaphus tragocamelus (Nilgai)

Code	Product Name	Source
CSB-YP624757BUN CSB-EP624757BUN CSB-BP624757BUN CSB-MP624757BUN CSB-EP624757BUN-B	Recombinant Boselaphus tragocamelus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Dasypus novemcinctus (Nine-banded armadillo)

Code	Product Name	Source
CSB-YP638463DIO CSB-EP638463DIO CSB-BP638463DIO CSB-MP638463DIO CSB-EP638463DIO-B	Recombinant Dasypus novemcinctus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

Code	Product Name	Source
CSB-YP641730BAAW CSB-EP641730BAAW CSB-BP641730BAAW CSB-MP641730BAAW CSB-EP641730BAAW-B	Recombinant Bubalus carabanensis Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Tupaia tana (Large tree shrew)

Code	Product Name	Source
CSB-YP681498TBAL CSB-EP681498TBAL CSB-BP681498TBAL CSB-MP681498TBAL CSB-EP681498TBAL-B	Recombinant Tupaia tana Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Camelus bactrianus (Bactrian camel)

Code	Product Name	Source
CSB-YP745057CVZ CSB-EP745057CVZ CSB-BP745057CVZ CSB-MP745057CVZ CSB-EP745057CVZ-B	Recombinant Camelus bactrianus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP808498EQV CSB-EP808498EQV CSB-BP808498EQV CSB-MP808498EQV CSB-EP808498EQV-B	Recombinant Pan troglodytes Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Sparus aurata (Gilthead sea bream)

Code	Product Name	Source
CSB-YP812922FJX CSB-EP812922FJX CSB-BP812922FJX CSB-MP812922FJX CSB-EP812922FJX-B	Recombinant Sparus aurata Tumor necrosis factor(tnf),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Saimiri sciureus (Common squirrel monkey)

Code	Product Name	Source
CSB-YP839752SWD CSB-EP839752SWD CSB-BP839752SWD CSB-MP839752SWD CSB-EP839752SWD-B	Recombinant Saimiri sciureus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Delphinapterus leucas (Beluga whale)

Code	Product Name	Source
CSB-YP855454DJB CSB-EP855454DJB CSB-BP855454DJB CSB-MP855454DJB CSB-EP855454DJB-B	Recombinant Delphinapterus leucas Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)

Code	Product Name	Source
CSB-YP858988TRF CSB-EP858988TRF CSB-BP858988TRF CSB-MP858988TRF CSB-EP858988TRF-B	Recombinant Tursiops truncatus Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-AP002141HU	Recombinant Human Tumor necrosis factor protein(TNF),partial (Active)	E.coli
CSB-AP002151HU	Recombinant Human Tumor necrosis factor protein(TNF),partial (Active)	E.coli
CSB-AP002161HU	Recombinant Human Tumor necrosis factor protein(TNF),partial (Active)	E.Coli
CSB-YP023955HU	Recombinant Human Tumor necrosis factor(TNF),partial (Active)	Yeast
CSB-EP023955HUc7	Recombinant Human Tumor necrosis factor(TNF),partial (Active)	E.coli
CSB-AP004861HU	Recombinant Human Tumor necrosis factor(TNF),partial (Active)	E.coli
CSB-AP004871HU	Recombinant Human Tumor necrosis factor(TNF),partial (Active)	E.coli
CSB-AP004881HU	Recombinant Human Tumor necrosis factor(TNF),partial (Active)	E.coli
CSB-AP005891HU	Recombinant Human Tumor Necrosis Factor-alpha/TNFSF2(TNF),partial (Active) (GMP)	E.Coli
CSB-EP023955HU	Recombinant Human Tumor necrosis factor(TNF),partial	E.coli

TNF Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-AP003221MOW	Recombinant Macaca mulatta Tumor necrosis factor protein(TNF),partial,(Active)	E.Coli
CSB-CF023955MOW	Recombinant Macaca mulatta Tumor necrosis factor(TNF)	in vitro E.coli expression system
CSB-YP023955MOW1 CSB-EP023955MOW1 CSB-BP023955MOW1 CSB-MP023955MOW1 CSB-EP023955MOW1-B	Recombinant Macaca mulatta Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-CF023955PI	Recombinant Pig Tumor necrosis factor(TNF)	in vitro E.coli expression system
CSB-YP023955PI1 CSB-EP023955PI1 CSB-BP023955PI1 CSB-MP023955PI1 CSB-EP023955PI1-B	Recombinant Pig Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-CF023955CA	Recombinant Cat Tumor necrosis factor(TNF)	in vitro E.coli expression system
CSB-YP023955CA1 CSB-EP023955CA1 CSB-BP023955CA1 CSB-MP023955CA1 CSB-EP023955CA1-B	Recombinant Cat Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Capra hircus (Goat)

Code	Product Name	Source
CSB-CF023955GO	Recombinant Goat Tumor necrosis factor(TNF)	in vitro E.coli expression system
CSB-YP023955GO1 CSB-EP023955GO1 CSB-BP023955GO1 CSB-MP023955GO1 CSB-EP023955GO1-B	Recombinant Goat Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-CF023955HO	Recombinant Horse Tumor necrosis factor(TNF)	in vitro E.coli expression system
CSB-YP023955HO1 CSB-EP023955HO1 CSB-BP023955HO1 CSB-MP023955HO1 CSB-EP023955HO1-B	Recombinant Horse Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNF Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-CF023955RB	Recombinant Rabbit Tumor necrosis factor(TNF)	in vitro E.coli expression system
CSB-YP023955RB1 CSB-EP023955RB1 CSB-BP023955RB1 CSB-MP023955RB1 CSB-EP023955RB1-B	Recombinant Rabbit Tumor necrosis factor(TNF),partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP005051RB	Recombinant Rabbit Tumor necrosis factor(TNF),partial (Active)	E.coli

TNF ELISA Kit

TNF ELISA Kit for Bos taurus (Bovine)

Code	Product Name	Sample Types	Sensitivity
CSB-E12020B	Bovine TNF-αELISA kit	serum, plasma, tissue homogenates	0.05 ng/mL

TNF ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Sample Types	Sensitivity
CSB-E11737c	Dog Tumor necrosis factor α,TNF-α ELISA Kit	serum, plasma, tissue homogenates	0.039 ng/mL

TNF ELISA Kit for Capra hircus (Goat)

Code	Product Name	Sample Types	Sensitivity
CSB-E09811g	Goat Tumor necrosis factor α,TNF-α ELISA KIT	serum, plasma, tissue homogenates	3.9 pg/mL

TNF ELISA Kit for Cavia porcellus (Guinea pig)

Code	Product Name	Sample Types	Sensitivity
CSB-E06772Gu	Guinea pig Tumor necrosis factor α,TNF-α ELISA Kit	serum, plasma, tissue homogenates	0.78 pg/mL

TNF ELISA Kit for Equus caballus (Horse)

Code	Product Name	Sample Types	Sensitivity
CSB-E14031Hs	Horse Tumor necrosis factor α,TNF-α ELISA Kit	serum, plasma, tissue homogenates	3.9 pg/mL

TNF ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E04740h	Human Tumor necrosis factor α,TNF-α ELISA KIT	serum, plasma, cell culture supernates, tissue homogenates, cell lysates	1.95 pg/mL

TNF ELISA Kit for Monkey

Code	Product Name	Sample Types	Sensitivity
CSB-E10039Mo	Monkey Tumor necrosis factor α,TNF-α ELISA KIT	serum, plasma, tissue homogenates	0.39 pg/mL

TNF ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-E04741m	Mouse Tumor necrosis factor α,TNF-α ELISA KIT	serum, plasma, cell culture supernates, tissue homogenates	3.9 pg/ml
CSB-E04741m(1)	Mouse Tumor necrosis factor α,TNF-α ELISA KIT	cell culture supernates, tissue homogenates	15.6 pg/mL

TNF ELISA Kit for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Sample Types	Sensitivity
CSB-E06998Rb	Rabbit Tumor necrosis factor α,TNFα ELISA Kit	serum, plasma, tissue homogenates, cell lysates	19.5 pg/mL

TNF ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-E11987r	Rat TNF-α ELISA kit	serum, plasma, cell culture supernates, tissue homogenates	1.56 pg/mL

TNF ELISA Kit for Ovis aries (Sheep)

Code	Product Name	Sample Types	Sensitivity
CSB-E13853Sh	Sheep Tumor Necrosis Factor α,TNF-α ELISA Kit	serum, plasma, tissue homogenates	3.125 pg/mL

TNF ELISA Kit for Sus scrofa (Pig)

Code	Product Name	Sample Types	Sensitivity
CSB-E16980p	Pig Tumor necrosis factor (TNF/TNFA/TNFSF2) ELISA kit	serum, plasma, cell culture supernates, tissue homogenates	0.040 ng/mL

TNF Background

Tumor necrosis factor is a protein in humans that is encoded by TNF gene. As a cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions, it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective.

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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