ipaC Antibody

Rare Species
Code CSB-PA324678ZA01SZB
Size US$299
Image
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes:ipaC Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 46.2 kDa
    Observed band size: 47 kDa
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Product Details

Full Product Name
Rabbit anti-Shigella flexneri ipaC Antibody Polyclonal antibody
Uniprot No.
Target Names
ipaC Antibody
Alternative Names
Invasin IpaC (42 kDa antigen), ipaC
Raised in
Rabbit
Species Reactivity
Shigella flexneri
Immunogen
Recombinant Shigella flexneri ipaC protein (1-363aa)
Immunogen Species
Shigella flexneri
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Forms a pore with IpaB, which is inserted into host cell membrane through the Mxi/Spa apparatus, during cell contact. This pore probably allows the translocation of IpaA. The C-terminus of IpaC could be involved in actin polymerization that leads to the cell extension formation and its N-terminus could be involved in the conversion of filopodial extensions into lamellipodial extension. Most extensions results from Cdc42 activation by IpaC whereas the lamellipodial extensions result from the Rac activation by Cdc42.
Subcellular Location
Secreted. Note=Secreted through the specialized type-III secretion system Mxi/Spa. Inserted into the host cell membrane.
Protein Families
Invasin protein C family
Database Links

KEGG: sfl:CP0127

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