Fibroblast growth factor receptor 3 is a protein in humans that is encoded by FGFR3 gene. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear. Phosphorylates PLCG1, CBL and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.
The following FGFR3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FGFR3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008646LA01HU | FGFR3 Antibody |
Human | ELISA, IHC, IF |
CSB-PA008646LC01HU | FGFR3 Antibody, FITC conjugated |
Human | |
CSB-PA008646LD01HU | FGFR3 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA164777 | FGFR3 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA008248 | FGFR3 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA114336 | FGFR3 Antibody |
Human,Mouse | ELISA,IHC |
CSB-RA555849A0HU | FGFR3 Recombinant Monoclonal Antibody |
Human | ELISA, IF |
CSB-RA966627A0HU | FGFR3 Recombinant Monoclonal Antibody |
Human | ELISA, WB |
FGFR3 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008646XA01DIL | fgfr3 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
FGFR3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP008646HU | Recombinant Human Fibroblast growth factor receptor 3 (FGFR3), partial |
Yeast |
CSB-YP008646HU(A4) | Recombinant Human Fibroblast growth factor receptor 3 (FGFR3), partial |
Yeast |
CSB-BP008646HU CSB-MP008646HU CSB-EP008646HU-B |
Recombinant Human Fibroblast growth factor receptor 3 (FGFR3), partial |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP008646HU | Recombinant Human Fibroblast growth factor receptor 3 (FGFR3), partial |
E.coli |
CSB-EP008646HU(A4) | Recombinant Human Fibroblast growth factor receptor 3 (FGFR3), partial |
E.coli |
CSB-AP003871HU | Recombinant Human Fibroblast growth factor receptor 3 (FGFR3), partial (Active) |
Mammalian cell |
FGFR3 Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP008646XBE CSB-EP008646XBE CSB-BP008646XBE CSB-MP008646XBE CSB-EP008646XBE-B |
Recombinant Xenopus laevis Fibroblast growth factor receptor 3 (fgfr3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP008646MO CSB-EP008646MO CSB-BP008646MO CSB-MP008646MO CSB-EP008646MO-B |
Recombinant Mouse Fibroblast growth factor receptor 3 (Fgfr3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR3 Proteins for Pleurodeles waltl (Iberian ribbed newt)
Code | Product Name | Source |
---|---|---|
CSB-YP008646EWZ CSB-EP008646EWZ CSB-BP008646EWZ CSB-MP008646EWZ CSB-EP008646EWZ-B |
Recombinant Pleurodeles waltl Fibroblast growth factor receptor 3 (FGFR3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR3 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Source |
---|---|---|
CSB-YP008646DIL CSB-EP008646DIL CSB-BP008646DIL CSB-MP008646DIL CSB-EP008646DIL-B |
Recombinant Danio rerio Fibroblast growth factor receptor 3 (fgfr3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR3 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-CF008646CH | Recombinant Chicken Fibroblast growth factor receptor 3 (FGFR3) |
in vitro E.coli expression system |
CSB-YP008646CH1 CSB-EP008646CH1 CSB-BP008646CH1 CSB-MP008646CH1 CSB-EP008646CH1-B |
Recombinant Chicken Fibroblast growth factor receptor 3 (FGFR3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR3 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL008646HU | Human Fibroblast growth factor receptor 3(FGFR3) ELISA kit |
serum, plasma, tissue homogenates | 15.6 pg/mL |