PRDX1

Peroxiredoxin 1 (PRDX1) is a member of the peroxiredoxin family of antioxidant enzymes, also known as natural killer cell-enhancing factor A (NKEF-A). It regulates cellular redox homeostasis by catalyzing the reduction of hydrogen peroxide and organic hydroperoxides using thioredoxin as a cofactor. PRDX1 participates in signaling pathways such as the NF-κB and p53 pathways, modulating inflammation and cell survival.
Dysregulation of PRDX1 is linked to cancer progression, cardiovascular diseases, and neurodegenerative disorders. Its overexpression in tumors correlates with poor prognosis, making it a potential therapeutic target. Small-molecule inhibitors targeting PRDX1's peroxidase activity are under preclinical evaluation for cancer treatment, with emerging evidence supporting their efficacy in suppressing tumor growth.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PRDX1 Antibody (CSB-PA01165A0Rb)

Validated Data

Western blot
All lanes: PRDX1 antibody at 2µg/ml
Lane 1: EC109 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 23 kDa
Observed band size: 23 kDa

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA01165A0Rb at dilution of 1:50

Immunofluorescent analysis of HepG2 cells using CSB-PA01165A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Peroxiredoxin-1(PRDX1) ELISA kit (CSB-EL018653HU)

Validated Data

Code: CSB-EL018653HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.78 ng/mL

Detection Range: 3.12 ng/mL-200 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following PRDX1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PRDX1 Antibodies

PRDX1 Proteins

PRDX1 ELISA Kits

PRDX1 Antibodies

PRDX1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA018653GA01HU	PRDX1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA01165D0Rb	PRDX1 Antibody, Biotin conjugated	Human	ELISA
CSB-PA01165A0Rb	PRDX1 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA01165C0Rb	PRDX1 Antibody, FITC conjugated	Human
CSB-PA018653ESR2HU	PRDX1 Antibody	Human	ELISA, WB, IHC
CSB-PA018653ESR1HU	PRDX1 Antibody	Human	ELISA, IHC
CSB-MA000271	PRDX1 Monoclonal Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA005818	PRDX1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA080143	PRDX1 Antibody	Human,Mouse,Rat	WB, IHC
CSB-PA912013	PRDX1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA780249	PRDX1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-RA947589A0HU	PRDX1 Recombinant Monoclonal Antibody	Human	ELISA, IHC, FC

PRDX1 Antibodies for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Code	Product Name	Species Reactivity	Application
CSB-PA872876ZA01DXU	PRDX1 Antibody	Cricetulus griseus	ELISA, WB (ensure identification of antigen)

PRDX1 Proteins

PRDX1 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP018653CH CSB-EP018653CH CSB-BP018653CH CSB-MP018653CH CSB-EP018653CH-B	Recombinant Chicken Peroxiredoxin-1 (PRDX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PRDX1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP018653MO CSB-EP018653MO CSB-BP018653MO CSB-MP018653MO CSB-EP018653MO-B	Recombinant Mouse Peroxiredoxin-1 (Prdx1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PRDX1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP685708BO CSB-EP685708BO CSB-BP685708BO CSB-MP685708BO CSB-EP685708BO-B	Recombinant Bovine Peroxiredoxin-1 (PRDX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PRDX1 Proteins for Gekko japonicus (Schlegel's Japanese gecko)

Code	Product Name	Source
CSB-YP718795GEG CSB-EP718795GEG CSB-BP718795GEG CSB-MP718795GEG CSB-EP718795GEG-B	Recombinant Gecko japonicus Peroxiredoxin-1 (PRDX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PRDX1 Proteins for Myotis lucifugus (Little brown bat)

Code	Product Name	Source
CSB-YP724533MWS CSB-EP724533MWS CSB-BP724533MWS CSB-MP724533MWS CSB-EP724533MWS-B	Recombinant Myotis lucifugus Peroxiredoxin-1 (PRDX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PRDX1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP737225RA CSB-EP737225RA CSB-BP737225RA CSB-MP737225RA CSB-EP737225RA-B	Recombinant Rat Peroxiredoxin-1 (Prdx1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PRDX1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Code	Product Name	Source
CSB-BP872876DXU CSB-MP872876DXU CSB-EP872876DXU-B	Recombinant Cricetulus griseus Peroxiredoxin-1 (PRDX1)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP872876DXU	Recombinant Cricetulus griseus Peroxiredoxin-1 (PRDX1)	E.coli
CSB-YP872876DXU	Recombinant Cricetulus griseus Peroxiredoxin-1 (PRDX1)	Yeast

PRDX1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-EP018653HUe0	Recombinant Human Peroxiredoxin-1 (PRDX1)	E.coli
CSB-EP018653HU	Recombinant Human Peroxiredoxin-1 (PRDX1)	E.coli
CSB-YP018653HU	Recombinant Human Peroxiredoxin-1 (PRDX1)	Yeast
CSB-YP018653HUa0	Recombinant Human Peroxiredoxin-1 (PRDX1)	Yeast

PRDX1 ELISA Kit

PRDX1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL018653HU	Human Peroxiredoxin-1(PRDX1) ELISA kit	serum, plasma, tissue homogenates, cell lysates	0.78 ng/mL

PRDX1 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL018653MO	Mouse Peroxiredoxin-1(PRDX1) ELISA kit	serum, plasma, tissue homogenates	0.078 ng/mL

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PRDX1

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