S100A8, also known as calgranulin A or myeloid-related protein 8 (MRP8), is a calcium-binding protein belonging to the S100 family. It forms a heterodimer with S100A9, which is involved in regulating inflammation and immune responses. The S100A8/A9 complex can bind to receptors like RAGE, triggering intracellular signaling pathways such as NF-κB.
S100A8 is associated with various diseases, including rheumatoid arthritis, inflammatory bowel disease, and cancer. Elevated levels of S100A8 are often found in patients with these conditions. Currently, there are ongoing efforts in drug development to target S100A8 and its signaling pathways, aiming to alleviate inflammation and treat related diseases.
S100A8 Monoclonal Antibody (CSB-MA0206411A0m)
Validated Data
Immunohistochemical of paraffin-embedded human cervical cancer using CSB-MA0206411A0m at dilution of 1:200
Immunohistochemical of paraffin-embedded human spleen using CSB-MA0206411A0m at dilution of 1:200
Human S100 calcium binding protein A8/calgranulin A,S100A8 ELISA Kit (CSB-E11833h)
Validated Data
Code: CSB-E11833h
Size: 96T,5×96T,10×96T
Sensitivity: 0.31 ng/mL
Detection Range: 1.25 ng/mL-80 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following S100A8 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
S100A8 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020641HA01HU | S100A8 Antibody | Human | ELISA, IHC |
CSB-PA020641HB01HU | S100A8 Antibody, HRP conjugated | Human | ELISA |
CSB-PA020641HD01HU | S100A8 Antibody, Biotin conjugated | Human | ELISA |
CSB-MA0206411A0m | S100A8 Monoclonal Antibody | Human | ELISA,IHC |
CSB-PA020641GA01HU | S100A8 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
S100A8 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020641DA01MO | S100a8 Antibody | Mouse | ELISA, WB |
CSB-PA020641DC01MO | S100a8 Antibody, FITC conjugated | Mouse | |
CSB-PA020641DD01MO | S100a8 Antibody, Biotin conjugated | Mouse | ELISA |
CSB-PA020641HA01MO | S100a8 Antibody | Mouse | ELISA |
S100A8 Antibodies for Rattus norvegicus (Rat)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020641LA01RA | S100a8 Antibody | Rat | ELISA, WB |
CSB-PA020641LD01RA | S100a8 Antibody, Biotin conjugated | Rat | ELISA |
S100A8 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP020641MO | Recombinant Mouse Protein S100-A8 (S100a8) | Yeast |
CSB-EP020641MO | Recombinant Mouse Protein S100-A8 (S100a8) | E.coli |
CSB-BP020641MO CSB-MP020641MO CSB-EP020641MO-B |
Recombinant Mouse Protein S100-A8 (S100a8) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP020641MOe0 | Recombinant Mouse Protein S100-A8 (S100a8) | E.coli |
S100A8 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP020641BO CSB-EP020641BO CSB-BP020641BO CSB-MP020641BO CSB-EP020641BO-B |
Recombinant Bovine Protein S100-A8 (S100A8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
S100A8 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-EP020641RA | Recombinant Rat Protein S100-A8 (S100a8) | E.coli |
CSB-YP20641RA CSB-EP20641RA CSB-BP20641RA CSB-MP20641RA CSB-EP20641RA-B |
Recombinant rat Protein S100-A8 | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP020641RA | Recombinant Rat Protein S100-A8 (S100a8) | Yeast |
CSB-BP020641RA CSB-MP020641RA CSB-EP020641RA-B |
Recombinant Rat Protein S100-A8 (S100a8) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
S100A8 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP020641HU CSB-EP020641HU CSB-BP020641HU CSB-MP020641HU CSB-EP020641HU-B |
Recombinant Human Protein S100-A8 (S100A8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
S100A8 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E11833h | Human S100 calcium binding protein A8/calgranulin A,S100A8 ELISA Kit | serum, plasma, tissue homogenates | 0.31 ng/mL |
S100A8 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL020641MO | Mouse S100 calcium binding protein A8 (S100A8) ELISA kit | serum, plasma, tissue homogenates. | 2.7 ng/ml. |
S100A8 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL020641RA | Rat Protein S100-A8(S100A8) ELISA kit | serum, plasma, tissue homogenates | 0.78 ng/mL |