TFPI

TFPI (Tissue Factor Pathway Inhibitor) is a protein that plays a crucial role in the blood clotting process. It is one of the primary endogenous anticoagulant proteins and is employed to inhibit the tissue factor pathway during coagulation. It typically exists in multiple subtypes, with the main subtypes being TFPIα and TFPIβ. The primary function of TFPI is to inhibit the tissue factor pathway of blood coagulation, which is a mechanism that triggers blood clotting and typically occurs in damaged or injured blood vessels. TFPI is a critical factor in maintaining the balance of normal blood coagulation. Its presence and function help prevent abnormal or excessive clotting, thereby reducing the risk of thrombus formation and vascular blockages. Research on TFPI contributes to a better understanding of the regulation of blood clotting mechanisms and the pathogenesis of diseases related to thrombosis and bleeding.

More Interesting read related TFPI: a Natural Anticoagulant Protein, Future Therapies for Hemophilia

Popular Product

● Recombinant Human Tissue factor pathway inhibitor(TFPI),partial (Active) CSB-MP023437HU

Validated Data

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TFPI at 1 μg/ml can bind Anti-TFPI recombinant antibody (CSB-RA023437MA01HU), the EC₅₀ is 1.242-1.788 ng/mL.

● Recombinant Rabbit Tissue factor pathway inhibitor(TFPI) (Active) CSB-MP023437RB

Validated Data

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Rabbit TFPI at 1 μg/ml can bind Anti-TFPI recombinant antibody (CSB-RA023437MA01HU), the EC₅₀ is 2.281-3.783 ng/mL.