TNFSF9

TNFSF9, also known as TNF Superfamily Member 9, is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It acts as a ligand for TNFRSF9/4-1BB, a costimulatory receptor on T lymphocytes, and is involved in antigen presentation and cytotoxic T cell generation. TNFSF9 signaling promotes T cell proliferation and activation, and is associated with immune responses in various diseases, including cancer and autoimmune disorders. The TNFSF9/4-1BB pathway is a potential target for cancer immunotherapy, with ongoing research exploring its role in tumor immune microenvironment and its implications for drug development.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized TNFSF9 at 2 μg/ml can bind TNFRSF9（CSB-MP023984HU1）, the EC₅₀ is 2.671-3.702 ng/mL.

TNFSF9 Antibody (CSB-PA08047A0Rb)

Validated Data

Immunofluorescence staining of Hela cells with CSB-PA08047A0Rb at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA08047A0Rb at dilution of 1:100

Human Tumor necrosis factor ligand superfamily member 9(TNFSF9) ELISA kit (CSB-EL023997HU)

Validated Data

Code: CSB-EL023997HU

Size: 96T,5×96T,10×96T

Sensitivity: 4.7 pg/mL

Detection Range: 18.75 pg/mL-1200 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following TNFSF9 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TNFSF9 Antibodies

TNFSF9 Proteins

TNFSF9 ELISA Kits

TNFSF9 Antibodies

TNFSF9 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA08047A0Rb	TNFSF9 Antibody	Human	ELISA, IHC, IF
CSB-PA08047B0Rb	TNFSF9 Antibody, HRP conjugated	Human	ELISA
CSB-PA203832	TNFSF9 Antibody	Human	ELISA,WB,IF
CSB-PA001424	TNFSF9 Antibody	Human	IF, ELISA

TNFSF9 Proteins

TNFSF9 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP023997HU CSB-EP023997HU CSB-BP023997HU CSB-MP023997HU CSB-EP023997HU-B	Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001961HU	Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial (Active)	E.coli
CSB-CF023997HU(A4)	Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9)	in vitro E.coli expression system
CSB-RP080474h	Recombinant Human Tumor necrosis factor ligand superfamily member 9 protein (TNFSF9), partial	E.coli
CSB-MP023997HU1	Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial (Active)	Mammalian cell
CSB-MP023997HU-B	Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial, Biotinylated	Mammalian cell
CSB-MP023997HU1a0	Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial	Mammalian cell

TNFSF9 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF023997MO	Recombinant Mouse Tumor necrosis factor ligand superfamily member 9 (Tnfsf9)	in vitro E.coli expression system
CSB-YP023997MO1 CSB-EP023997MO1 CSB-BP023997MO1 CSB-MP023997MO1 CSB-EP023997MO1-B	Recombinant Mouse Tumor necrosis factor ligand superfamily member 9 (Tnfsf9), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNFSF9 ELISA Kit

TNFSF9 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL023997HU	Human Tumor necrosis factor ligand superfamily member 9(TNFSF9) ELISA kit	serum, plasma, tissue homogenates	4.7 pg/mL

TNFSF9 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL023997MO	Mouse Tumor necrosis factor ligand superfamily member 9(TNFSF9) ELISA kit	serum, plasma, tissue homogenates	5.8 pg/mL

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TNFSF9

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