VCAM1

Vascular Cell Adhesion Molecule 1 (VCAM1), also known as CD106, is a type I transmembrane glycoprotein expressed on the surface of endothelial cells. It plays a critical role in leukocyte recruitment and adhesion during inflammation by binding to integrin α4β1 (VLA-4) on leukocytes. VCAM1 is involved in various inflammatory processes, including atherosclerosis, where it contributes to the development of plaques by facilitating monocyte infiltration into the arterial wall. The VCAM1/VLA-4 interaction is regulated by various signaling pathways, such as the NF-κB and MAPK pathways, and is a target for drug development in the treatment of inflammatory diseases. Recent research has focused on the development of VCAM1 inhibitors, including monoclonal antibodies and small molecule inhibitors, to treat atherosclerosis and other inflammatory conditions.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

VCAM1 Antibody (CSB-PA078497)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA078497(VCAM1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA078497(VCAM1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

Human Vascular cell adhesion molecule 1,VCAM-1 ELISA kit (CSB-E04753h)

Validated Data

Code: CSB-E04753h

Size: 96T,5×96T,10×96T

Sensitivity: 0.611 ng/mL

Detection Range: 1.563 ng/mL-100 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following VCAM1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

VCAM1 Antibodies

VCAM1 Proteins

VCAM1 ELISA Kits

VCAM1 Antibodies

VCAM1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA025809GA01HU	VCAM1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA025809LA01HU	VCAM1 Antibody	Human	ELISA
CSB-PA025809LB01HU	VCAM1 Antibody, HRP conjugated	Human	ELISA
CSB-PA025809LC01HU	VCAM1 Antibody, FITC conjugated	Human
CSB-PA078497	VCAM1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA213301	VCAM1 Antibody	Human,Mouse,Rat	ELISA,IHC

VCAM1 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA025809ZA01RA	Vcam1 Antibody	Rattus norvegicus	ELISA, WB (ensure identification of antigen)

VCAM1 Proteins

VCAM1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP025809HU	Recombinant Human Vascular cell adhesion protein 1 (VCAM1), partial	Yeast
CSB-BP025809HU CSB-MP025809HU CSB-EP025809HU-B	Recombinant Human Vascular cell adhesion protein 1 (VCAM1)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP025809HU	Recombinant Human Vascular cell adhesion protein 1 (VCAM1), partial	E.coli

VCAM1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP025809RA CSB-EP025809RA CSB-BP025809RA CSB-MP025809RA CSB-EP025809RA-B	Recombinant Rat Vascular cell adhesion protein 1 (Vcam1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF025809RA(A4)	Recombinant Rat Vascular cell adhesion protein 1 (Vcam1)	in vitro E.coli expression system
CSB-EP025809RA1	Recombinant Rat Vascular cell adhesion protein 1 (Vcam1), partial	E.coli

VCAM1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP637896DO CSB-EP637896DO CSB-BP637896DO CSB-MP637896DO CSB-EP637896DO-B	Recombinant Dog Vascular cell adhesion protein 1 (VCAM1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

VCAM1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF025809MO	Recombinant Mouse Vascular cell adhesion protein 1 (Vcam1)	in vitro E.coli expression system
CSB-YP025809MO1 CSB-EP025809MO1 CSB-BP025809MO1 CSB-MP025809MO1 CSB-EP025809MO1-B	Recombinant Mouse Vascular cell adhesion protein 1 (Vcam1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli