ATG3

Ubiquitin-like-conjugating enzyme ATG3 is a protein in humans that is encoded by ATG3 gene. E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy.

ATG3 Antibodies

ATG3 Antibodies for Homo sapiens (Human)

ATG3 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

ATG3 Proteins

ATG3 Proteins for Bos taurus (Bovine)

ATG3 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

ATG3 Proteins for Rattus norvegicus (Rat)

ATG3 Proteins for Xenopus laevis (African clawed frog)

ATG3 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

ATG3 Proteins for Mus musculus (Mouse)

ATG3 Proteins for Homo sapiens (Human)

ATG3 cDNA for Danio rerio (Zebrafish) (Brachydanio rerio)

Code Product Name Vector Accession NO.
CSB-CL761343DIL apg3l pUC NM_200022.1

ATG3 cDNA for Mus musculus (Mouse)

Code Product Name Vector Accession NO.
CSB-CL863407MO Atg3 pUC NM_026402.3

ATG3 cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL889107HU1 ATG3 pUC NM_022488.3

ATG3 ELISA Kit

ATG3 ELISA Kit for Homo sapiens (Human)

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