GLP-1R (Glucagon-Like Peptide-1 Receptor) is a receptor protein belonging to the G protein-coupled receptor family. It is a receptor that interacts with glucagon-like peptide-1 (GLP-1) and plays a critical physiological role in insulin secretion and blood glucose regulation. GLP-1R is located on pancreatic beta cells, and when GLP-1 binds to GLP-1R, it can stimulate the secretion of insulin. In addition to promoting insulin secretion, GLP-1R also inhibits the secretion of glucagon. GLP-1 receptor agonists are a class of drugs commonly used to treat type 2 diabetes. They mimic the action of GLP-1, stimulating insulin secretion and inhibiting glucagon, thereby lowering blood sugar levels. Research on GLP-1R is of significant importance in understanding diseases related to insulin secretion and blood glucose regulation.
Recombinant Human Glucagon-like peptide 1 receptor(GLP1R),partial (Active) CSB-MP009514HUb1
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GLP1R at 2 μg/mL can bind Anti-GLP1R recombinant antibody (CSB-RA009514MA1HU), the EC50 is 54.54-94.23 ng/mL.
The following GLP1R reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GLP1R Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009514LD01HU | GLP1R Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA009514YA01HU | GLP1R Antibody |
Human, Mouse | ELISA, WB, IF |
CSB-PA009514YB01HU | GLP1R Antibody, HRP conjugated |
Human | ELISA |
CSB-PA009514YD01HU | GLP1R Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA009514LA01HU | GLP1R Antibody |
Human | ELISA, WB, IHC, IF |
CSB-PA002699 | GLP1R Antibody |
Human,Mouse | WB, IF, ELISA |
CSB-PA183226 | GLP1R Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-RA009514MA1HU | GLP1R Recombinant Monoclonal Antibody |
Human | ELISA, FC |
GLP1R Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009514HA01MO | Glp1r Antibody |
Mouse | ELISA, WB |
CSB-PA009514HB01MO | Glp1r Antibody, HRP conjugated |
Mouse | ELISA |
CSB-PA009514HC01MO | Glp1r Antibody, FITC conjugated |
Mouse | |
CSB-PA009514HD01MO | Glp1r Antibody, Biotin conjugated |
Mouse | ELISA |
GLP1R Antibodies for Rattus norvegicus (Rat)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009514ZA01RA | Glp1r Antibody |
Rattus norvegicus | ELISA, WB (ensure identification of antigen) |
GLP1R Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP009514HU | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R), partial |
E.coli |
CSB-BP009514HU | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R), partial |
Baculovirus |
CSB-MP009514HU | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R), partial |
Mammalian cell |
CSB-YP009514HU | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R), partial |
Yeast |
CSB-CF009514HU | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R) |
in vitro E.coli expression system |
CSB-CF009514HU(A4) | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R) |
in vitro E.coli expression system |
CSB-MP009514HU(A4) | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R)-VLPs |
Mammalian cell |
CSB-MP009514HUb1 | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R), partial (Active) |
Mammalian cell |
CSB-EP009514HUd7 | Recombinant Human Glucagon-like peptide 1 receptor (GLP1R), partial |
E.coli |
GLP1R Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF009514MO | Recombinant Mouse Glucagon-like peptide 1 receptor (Glp1r) |
in vitro E.coli expression system |
CSB-EP009514MO1 | Recombinant Mouse Glucagon-like peptide 1 receptor (Glp1r), partial |
E.coli |
CSB-YP009514MO1 CSB-BP009514MO1 CSB-MP009514MO1 CSB-EP009514MO1-B |
Recombinant Mouse Glucagon-like peptide 1 receptor (Glp1r), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GLP1R Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF009514RA | Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r) |
in vitro E.coli expression system |
CSB-EP009514RA CSB-MP009514RA CSB-EP009514RA-B |
Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial |
E.coli Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP009514RA | Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial |
Yeast |
CSB-BP009514RA | Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial |
Baculovirus |
CSB-BP009514RA1 | Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial |
Baculovirus |
CSB-MP009514RA1 CSB-EP009514RA1-B |
Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial |
Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP009514RA1 | Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial |
Yeast |
CSB-EP009514RA1 | Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial |
E.coli |
GLP1R ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL009514MO | Mouse Glucagon-like peptide 1 receptor(GLP1R) ELISA kit |
serum, plasma, tissue homogenates | 0.11 ng/ml |