P4HB Research Reagents

Protein disulfide-isomerase is a protein in humans that is encoded by P4HB gene. This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis.

The following P4HB reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

P4HB Antibodies

P4HB Antibodies for Homo sapiens (Human)

P4HB Antibodies for Mus musculus (Mouse)

P4HB Antibodies for Cricetulus griseus

P4HB Proteins

P4HB Proteins for Oryctolagus cuniculus (Rabbit)

P4HB Proteins for Bos taurus (Bovine)

P4HB Proteins for Homo sapiens (Human)

P4HB Proteins for Gallus gallus (Chicken)

P4HB Proteins for Mus musculus (Mouse)

P4HB Proteins for Rattus norvegicus (Rat)

P4HB Proteins for Macaca fuscata fuscata (Japanese macaque)

P4HB Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

P4HB Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

P4HB ELISA Kit

P4HB ELISA Kit for Homo sapiens (Human)

P4HB ELISA Kit for Mus musculus (Mouse)

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