PF4

PF4, also known as Platelet Factor 4, is a small cytokine belonging to the CXC chemokine family. It is also commonly referred to as CXCL4. PF4 is mainly released by activated platelets. Its mechanism involves binding to proteoglycans on cell surfaces and modulating cell - matrix interactions. It is involved in the heparin - platelet factor 4 complex signaling pathway.
PF4 is associated with several diseases, such as heparin - induced thrombocytopenia. In drug development, efforts are underway to target the PF4 - related pathways to develop therapies for these associated diseases. Some potential drugs are in pre - clinical trials to regulate its function and mitigate its adverse effects.

Validated Data

Code: CSB-EL017810HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.156 ng/mL

Detection Range: 0.625 ng/mL-40 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following PF4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PF4 Antibodies

PF4 Proteins

PF4 ELISA Kits

PF4 Antibodies

PF4 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA958757	PF4 Antibody	Human,Rat	IHC,ELISA
CSB-PA017809LA01HU	PF4 Antibody	Human	ELISA, IHC
CSB-PA017809LB01HU	PF4 Antibody, HRP conjugated	Human	ELISA
CSB-PA017809LC01HU	PF4 Antibody, FITC conjugated	Human
CSB-PA017809LD01HU	PF4 Antibody, Biotin conjugated	Human	ELISA

PF4 Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA017809ZA01MO	Pf4 Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

PF4 Proteins

PF4 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP017809RB CSB-EP017809RB CSB-BP017809RB CSB-MP017809RB CSB-EP017809RB-B	Recombinant Rabbit Platelet factor 4 (PF4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP017810HU CSB-EP017810HU CSB-BP017810HU CSB-MP017810HU CSB-EP017810HU-B	Recombinant Human Platelet factor 4 variant (PF4V1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-BP017809HU CSB-MP017809HU CSB-EP017809HU-B	Recombinant Human Platelet factor 4 (PF4)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP000661HU	Recombinant Human Platelet factor 4 protein (PF4)	E.Coli

PF4 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-BP017809PI CSB-MP017809PI CSB-EP017809PI-B	Recombinant Pig Platelet factor 4 (PF4)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP017809SH CSB-EP017809SH CSB-BP017809SH CSB-MP017809SH CSB-EP017809SH-B	Recombinant Sheep Platelet factor 4 (PF4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP017809BO CSB-EP017809BO CSB-BP017809BO CSB-MP017809BO CSB-EP017809BO-B	Recombinant Bovine Platelet factor 4 (PF4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP017809RA CSB-EP017809RA CSB-BP017809RA CSB-MP017809RA CSB-EP017809RA-B	Recombinant Rat Platelet factor 4 (Pf4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP017809MO CSB-BP017809MO CSB-MP017809MO CSB-EP017809MO-B	Recombinant Mouse Platelet factor 4 (Pf4)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001101MO	Recombinant Mouse Platelet factor 4 (Pf4) (Active)	E.coli
CSB-EP017809MO	Recombinant mouse platelet factor 4 (Pf4)	E.coli

PF4 ELISA Kit

PF4 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E07882h	Human Platelet Factor 4,PF-4 ELISA Kit	serum, plasma, tissue homogenates	1.56 ng/mL
CSB-EL017810HU	Human Platelet factor 4 variant(PF4V1) ELISA kit	serum, plasma, cell culture supernates, tissue homogenates	0.156 ng/mL