TIMP1

Metalloproteinase inhibitor 1 is a protein in humans that is encoded by TIMP1 gene. Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

The following TIMP1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TIMP1 Antibodies

TIMP1 Proteins

TIMP1 ELISA Kits

TIMP1 Antibodies

TIMP1 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-MA167191A0m	Timp1 Monoclonal Antibody	Rat	ELISA,IHC
CSB-PA16719A0Rb	Timp1 Antibody	Rat	ELISA
CSB-PA16719B0Rb	Timp1 Antibody, HRP conjugated	Rat	ELISA

TIMP1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-MA0235601A0m	TIMP1 Monoclonal Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA023560YA01HU	TIMP1 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA023560GA01HU	TIMP1 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA020114	TIMP1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA152790	TIMP1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA004293	TIMP1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA827458	TIMP1 Antibody	Human	ELISA,IHC
CSB-PA023560YB01HU	TIMP1 Antibody, HRP conjugated	Human	ELISA
CSB-PA023560YC01HU	TIMP1 Antibody, FITC conjugated	Human
CSB-PA023560YD01HU	TIMP1 Antibody, Biotin conjugated	Human	ELISA

TIMP1 Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA023560LA01MO	Timp1 Antibody	Mouse	ELISA
CSB-PA023560LB01MO	Timp1 Antibody, HRP conjugated	Mouse	ELISA
CSB-PA023560LD01MO	Timp1 Antibody, Biotin conjugated	Mouse	ELISA

TIMP1 Proteins

TIMP1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP023560DO CSB-EP023560DO CSB-BP023560DO CSB-MP023560DO CSB-EP023560DO-B	Recombinant Dog Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-EP023560MO	Recombinant Mouse Metalloproteinase inhibitor 1 (Timp1)	E.coli
CSB-YP023560MO CSB-BP023560MO CSB-MP023560MO CSB-EP023560MO-B	Recombinant Mouse Metalloproteinase inhibitor 1 (Timp1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP023560BO CSB-EP023560BO CSB-BP023560BO CSB-MP023560BO CSB-EP023560BO-B	Recombinant Bovine Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP023560RB CSB-EP023560RB CSB-BP023560RB CSB-MP023560RB CSB-EP023560RB-B	Recombinant Rabbit Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP023560PI CSB-EP023560PI CSB-BP023560PI CSB-MP023560PI CSB-EP023560PI-B	Recombinant Pig Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP023560SH CSB-EP023560SH CSB-BP023560SH CSB-MP023560SH CSB-EP023560SH-B	Recombinant Sheep Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP023560HO CSB-EP023560HO CSB-BP023560HO CSB-MP023560HO CSB-EP023560HO-B	Recombinant Horse Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP023560RA CSB-EP023560RA CSB-BP023560RA CSB-MP023560RA CSB-EP023560RA-B	Recombinant Rat Metalloproteinase inhibitor 1 (Timp1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-RP167194r	Recombinant Rat Metalloproteinase inhibitor 1 (Timp1)	E.coli

TIMP1 Proteins for Papio cynocephalus (Yellow baboon)

Code	Product Name	Source
CSB-YP023560PBR CSB-EP023560PBR CSB-BP023560PBR CSB-MP023560PBR CSB-EP023560PBR-B	Recombinant Papio cynocephalus Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP725402PYX CSB-EP725402PYX CSB-BP725402PYX CSB-MP725402PYX CSB-EP725402PYX-B	Recombinant Pongo abelii Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP839203MOW CSB-EP839203MOW CSB-BP839203MOW CSB-MP839203MOW CSB-EP839203MOW-B	Recombinant Macaca mulatta Metalloproteinase inhibitor 1 (TIMP1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TIMP1 ELISA Kit

TIMP1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E08003h	Human Tissue Inhibitor Of Matrix Metalloprotease-1 (TIMP-1) ELISA KIT	serum, plasma, tissue homogenates	0.434 ng/mL

TIMP1 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-E08004m	Mouse tissue inhibitors of metalloproteinase 1,TIMP-1 ELISA Kit	serum, plasma, cell culture supernates	0.110 ng/mL

TIMP1 ELISA Kit for Sus scrofa (Pig)

Code	Product Name	Sample Types	Sensitivity
CSB-E06799p	Pig tissue inhibitors of metalloproteinase 1,TIMP-1 ELISA Kit	serum, plasma, tissue homogenates	1.95 ng/mL

TIMP1 ELISA Kit for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Sample Types	Sensitivity
CSB-E06935Rb	Rabbit tissue inhibitors of metalloproteinase 1,TIMP-1 ELISA Kit	serum, plasma, cell culture supernates , tissue homogenates	7.8 pg/mL

TIMP1 ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-E08005r	Rat tissue inhibitors of metalloproteinase 1,TIMP-1 ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	0.224 ng/mL

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