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Mlc1 Antibody

Datasheet
Citations (1)
Code CSB-PA837739XA01MO
Size US$166
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Image
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes:Mlc1 Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 37 kDa
    Observed band size: 37 kDa
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Mlc1 Antibody Polyclonal antibody
Uniprot No.
Q8VHK5
Target Names
Mlc1 Antibody
Alternative Names
Membrane protein MLC1, Mlc1
Raised in
Rabbit
Species Reactivity
Mus musculus (Mouse)
Immunogen
Recombinant Mus musculus (Mouse) Mlc1 protein (331-382aa)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Related Products

Mlc1 Antibody Proteins

Customer Reviews and Q&A

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Target Background

Function
Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
Gene References into Functions
  1. Mlc1 overexpression reduced activity of the astrocytic sodium pump, which may underlie white matter edema followed by myelin membrane splitting PMID: 27748972
  2. This study demonistrated that Mlc1-null mice replicate the human with megalencephalic leukoencephalopathy with cysts. PMID: 25382142
  3. The complete cDNA sequence, exon-intron organization, and 5'-flanking regulatory region of murine Mlc1 have been reported. PMID: 12658361
  4. Because the temporal expression of Mlc1 indicates that, in contrast to developing and mature astrocytes, oligodendrocytes are devoid of Mlc1 expression, white matter tract abnormalities in these disorders may result from a primary astrocytic defect. PMID: 14603469
  5. Wkl1 is not associated with schizophrenia. PMID: 14755440
  6. Localization and functional analysis of Mlc1 were done in megalocephalic leukoencephalopathy with subcortical cysts. PMID: 15367490
  7. Our data provide a mouse MLC1 expression map that could be useful to understand the phenotype of MLC patients, and suggested that MLC disease is caused by an astrocytic and a neuronal dysfunction PMID: 17434314

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Subcellular Location
Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum.
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Related pathways
Inhibitors of axonal regeneration
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