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G1/S-specific cyclin-D1 is a protein in humans that is encoded by CCND1 gene. Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity.
CCND1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA004811LD01HU | CCND1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA004811LC01HU | CCND1 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA004811LB01HU | CCND1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA004811LA01HU | CCND1 Antibody | Human | ELISA |
| CSB-PA004811KA01HU | CCND1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,ICC,IP |
| CSB-PA184970 | Phospho-CCND1 (Thr286) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA963558 | Phospho-CCND1 (Ser90) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA000642 | Phospho-CCND1 (T286) Antibody | Human,Mouse,Rat | WB,IHC,ELISA |
| CSB-PA001875 | CCND1 Antibody | Human,Mouse,Rat | WB,IHC,ELISA |
| CSB-PA040188 | CCND1 Antibody | Human,Mouse,Rat | WB,ELISA |
| CSB-PA080258 | CCND1 Antibody | Rat,Mouse | WB,IHC |
| CSB-PA516472 | CCND1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA446984 | CCND1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA843257 | CCND1 Antibody | Human,Mouse,Rat | ELISA,IHC |
CCND1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA820871XA01DIL | CCND1 Antibody | Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
CCND1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004811HU CSB-BP004811HU CSB-MP004811HU |
Recombinant Human G1/S-specific cyclin-D1(CCND1) | Yeast Baculovirus Mammalian cell |
| CSB-EP004811HU | Recombinant Human G1/S-specific cyclin-D1(CCND1) | E.coli |
CCND1 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004811MO CSB-EP004811MO CSB-BP004811MO CSB-MP004811MO |
Recombinant Mouse G1/S-specific cyclin-D1(Ccnd1) | Yeast E.coli Baculovirus Mammalian cell |
CCND1 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004811RA CSB-EP004811RA CSB-BP004811RA CSB-MP004811RA |
Recombinant Rat G1/S-specific cyclin-D1(Ccnd1) | Yeast E.coli Baculovirus Mammalian cell |
CCND1 Proteins for Gallus gallus (Chicken)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004811CH CSB-EP004811CH CSB-BP004811CH CSB-MP004811CH |
Recombinant Chicken G1/S-specific cyclin-D1(CCND1) | Yeast E.coli Baculovirus Mammalian cell |
CCND1 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004811XBE CSB-EP004811XBE CSB-BP004811XBE CSB-MP004811XBE |
Recombinant Xenopus laevis G1/S-specific cyclin-D1(ccnd1) | Yeast E.coli Baculovirus Mammalian cell |
CCND1 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP645607BO CSB-EP645607BO CSB-BP645607BO CSB-MP645607BO |
Recombinant Bovine G1/S-specific cyclin-D1(CCND1) | Yeast E.coli Baculovirus Mammalian cell |
CCND1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP728931PYX CSB-EP728931PYX CSB-BP728931PYX CSB-MP728931PYX |
Recombinant Pongo abelii G1/S-specific cyclin-D1(CCND1) | Yeast E.coli Baculovirus Mammalian cell |
CCND1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP731088DO CSB-EP731088DO CSB-BP731088DO CSB-MP731088DO |
Recombinant Dog G1/S-specific cyclin-D1(CCND1) | Yeast E.coli Baculovirus Mammalian cell |
CCND1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP820871DIL CSB-EP820871DIL CSB-BP820871DIL CSB-MP820871DIL |
Recombinant Danio rerio G1/S-specific cyclin-D1(ccnd1) | Yeast E.coli Baculovirus Mammalian cell |
CCND1 cDNA for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
| Code | Product Name | Vector | Accession NO. |
|---|---|---|---|
| CSB-CL728931PYX | CCND1 | pUC | NM_001131301.1 |
CCND1 cDNA for Canis lupus familiaris (Dog) (Canis familiaris)
| Code | Product Name | Vector | Accession NO. |
|---|---|---|---|
| CSB-CL731088DO | CCND1 | pUC | NM_001005757.1 |
CCND1 cDNA for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Vector | Accession NO. |
|---|---|---|---|
| CSB-CL820871DIL | ccnd1 | pUC | NM_131025.4 |
CCND1 cDNA for Rattus norvegicus (Rat)
| Code | Product Name | Vector | Accession NO. |
|---|---|---|---|
| CSB-CL004811RA | Ccnd1 | pUC | NM_171992.4 |
CCND1 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E08286h | Human G1/S-specific Cyclin-D1 ELISA Kit | serum, plasma, cell culture supernates, cell lysates | 0.078 ng/mL |
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