CCND1

G1/S-specific cyclin-D1 is a protein in humans that is encoded by CCND1 gene. Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity.

CCND1 Antibodies

CCND1 Antibodies for Homo sapiens (Human)

Code Product Name Species Reactivity Application
CSB-PA004811LD01HU CCND1 Antibody, Biotin conjugated Human ELISA
CSB-PA004811LC01HU CCND1 Antibody, FITC conjugated Human ELISA
CSB-PA004811LB01HU CCND1 Antibody, HRP conjugated Human ELISA
CSB-PA004811LA01HU CCND1 Antibody Human ELISA
CSB-PA004811KA01HU CCND1 Antibody Human,Mouse,Rat ELISA,WB,IHC,ICC,IP
CSB-PA184970 Phospho-CCND1 (Thr286) Antibody Human,Mouse,Rat ELISA,WB
CSB-PA963558 Phospho-CCND1 (Ser90) Antibody Human,Mouse,Rat ELISA,WB
CSB-PA000642 Phospho-CCND1 (T286) Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA001875 CCND1 Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA040188 CCND1 Antibody Human,Mouse,Rat WB,ELISA
CSB-PA080258 CCND1 Antibody Rat,Mouse WB,IHC
CSB-PA516472 CCND1 Antibody Human,Mouse,Rat ELISA,WB,IHC
CSB-PA446984 CCND1 Antibody Human,Mouse,Rat ELISA,WB,IHC
CSB-PA843257 CCND1 Antibody Human,Mouse,Rat ELISA,IHC

CCND1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code Product Name Species Reactivity Application
CSB-PA820871XA01DIL CCND1 Antibody Danio rerio (Zebrafish) (Brachydanio rerio) ELISA, WB (ensure identification of antigen)

CCND1 Proteins

CCND1 Proteins for Homo sapiens (Human)

Code Product Name Source
CSB-YP004811HU Recombinant Human G1/S-specific cyclin-D1(CCND1),Yeast Yeast
CSB-EP004811HU Recombinant Human G1/S-specific cyclin-D1(CCND1) E.coli
CSB-BP004811HU Recombinant Human G1/S-specific cyclin-D1(CCND1),Baculovirus Baculovirus
CSB-MP004811HU Recombinant Human G1/S-specific cyclin-D1(CCND1),Mammalian cell Mammalian cell

CCND1 Proteins for Mus musculus (Mouse)

Code Product Name Source
CSB-YP004811MO Recombinant Mouse G1/S-specific cyclin-D1(Ccnd1),Yeast Yeast
CSB-EP004811MO Recombinant Mouse G1/S-specific cyclin-D1(Ccnd1),Escherichia Coli E.coli
CSB-BP004811MO Recombinant Mouse G1/S-specific cyclin-D1(Ccnd1),Baculovirus Baculovirus
CSB-MP004811MO Recombinant Mouse G1/S-specific cyclin-D1(Ccnd1),Mammalian cell Mammalian cell

CCND1 Proteins for Rattus norvegicus (Rat)

Code Product Name Source
CSB-YP004811RA Recombinant Rat G1/S-specific cyclin-D1(Ccnd1),Yeast Yeast
CSB-EP004811RA Recombinant Rat G1/S-specific cyclin-D1(Ccnd1),Escherichia Coli E.coli
CSB-BP004811RA Recombinant Rat G1/S-specific cyclin-D1(Ccnd1),Baculovirus Baculovirus
CSB-MP004811RA Recombinant Rat G1/S-specific cyclin-D1(Ccnd1),Mammalian cell Mammalian cell

CCND1 Proteins for Gallus gallus (Chicken)

Code Product Name Source
CSB-YP004811CH Recombinant Chicken G1/S-specific cyclin-D1(CCND1),Yeast Yeast
CSB-EP004811CH Recombinant Chicken G1/S-specific cyclin-D1(CCND1),Escherichia Coli E.coli
CSB-BP004811CH Recombinant Chicken G1/S-specific cyclin-D1(CCND1),Baculovirus Baculovirus
CSB-MP004811CH Recombinant Chicken G1/S-specific cyclin-D1(CCND1),Mammalian cell Mammalian cell

CCND1 Proteins for Xenopus laevis (African clawed frog)

Code Product Name Source
CSB-YP004811XBE Recombinant Xenopus laevis G1/S-specific cyclin-D1(ccnd1),Yeast Yeast
CSB-EP004811XBE Recombinant Xenopus laevis G1/S-specific cyclin-D1(ccnd1),Escherichia Coli E.coli
CSB-BP004811XBE Recombinant Xenopus laevis G1/S-specific cyclin-D1(ccnd1),Baculovirus Baculovirus
CSB-MP004811XBE Recombinant Xenopus laevis G1/S-specific cyclin-D1(ccnd1),Mammalian cell Mammalian cell

CCND1 Proteins for Bos taurus (Bovine)

Code Product Name Source
CSB-YP645607BO Recombinant Bovine G1/S-specific cyclin-D1(CCND1),Yeast Yeast
CSB-EP645607BO Recombinant Bovine G1/S-specific cyclin-D1(CCND1),Escherichia Coli E.coli
CSB-BP645607BO Recombinant Bovine G1/S-specific cyclin-D1(CCND1),Baculovirus Baculovirus
CSB-MP645607BO Recombinant Bovine G1/S-specific cyclin-D1(CCND1),Mammalian cell Mammalian cell

CCND1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code Product Name Source
CSB-YP728931PYX Recombinant Pongo abelii G1/S-specific cyclin-D1(CCND1),Yeast,Yeast Yeast
CSB-EP728931PYX Recombinant Pongo abelii G1/S-specific cyclin-D1(CCND1),Escherichia Coli E.coli
CSB-BP728931PYX Recombinant Pongo abelii G1/S-specific cyclin-D1(CCND1),Baculovirus Baculovirus
CSB-MP728931PYX Recombinant Pongo abelii G1/S-specific cyclin-D1(CCND1),Mammalian cell Mammalian cell

CCND1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code Product Name Source
CSB-YP731088DO Recombinant Dog G1/S-specific cyclin-D1(CCND1),Yeast Yeast
CSB-EP731088DO Recombinant Dog G1/S-specific cyclin-D1(CCND1),Escherichia Coli E.coli
CSB-BP731088DO Recombinant Dog G1/S-specific cyclin-D1(CCND1),Baculovirus Baculovirus
CSB-MP731088DO Recombinant Dog G1/S-specific cyclin-D1(CCND1),Mammalian cell Mammalian cell

CCND1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code Product Name Source
CSB-YP820871DIL Recombinant Danio rerio G1/S-specific cyclin-D1(ccnd1),Yeast Yeast
CSB-EP820871DIL Recombinant Danio rerio G1/S-specific cyclin-D1(ccnd1),Escherichia Coli E.coli
CSB-BP820871DIL Recombinant Danio rerio G1/S-specific cyclin-D1(ccnd1),Baculovirus Baculovirus
CSB-MP820871DIL Recombinant Danio rerio G1/S-specific cyclin-D1(ccnd1),Mammalian cell Mammalian cell

CCND1 cDNA

CCND1 cDNA for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code Product Name Vector Accession NO.
CSB-CL728931PYX CCND1 pUC NM_001131301.1

CCND1 cDNA for Canis lupus familiaris (Dog) (Canis familiaris)

Code Product Name Vector Accession NO.
CSB-CL731088DO CCND1 pUC NM_001005757.1

CCND1 cDNA for Danio rerio (Zebrafish) (Brachydanio rerio)

Code Product Name Vector Accession NO.
CSB-CL820871DIL ccnd1 pUC NM_131025.4

CCND1 cDNA for Rattus norvegicus (Rat)

Code Product Name Vector Accession NO.
CSB-CL004811RA Ccnd1 pUC NM_171992.4

CCND1 cDNA for Gallus gallus (Chicken)

Code Product Name Vector Accession NO.
CSB-CL004811CH CCND1 pUC NM_205381.1

CCND1 cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL004811HU CCND1 pUC NM_053056.2

CCND1 ELISA Kit

CCND1 ELISA Kit for Homo sapiens (Human)

Code Product Name Sample Types Sensitivity
CSB-E08286h Human G1/S-specific Cyclin-D1 ELISA Kit serum, plasma, cell culture supernates, cell lysates 0.078 ng/mL

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