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Delta-Like Ligand 3 (DLL3), a single transmembrane protein that attaches to the cell surface, is a member of the Notch ligand family. DDL3 is rarely expressed in normal tissues. But many findings suggested that DLL3 is highly expressed in SCLC and other neuroendocrine tumors, which offers potential for DLL3-targeted therapeutic design. In recent years, numerous studies have found that the ligand DLL3 inhibits Notch signaling pathway by binding to Notch receptors, affecting communication between neighboring cells and thus regulating cell development, whereas the specific mechanism has not yet been elucidated. In addition to the Notch signaling pathway, DLL3 also functions in other signaling pathways.
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Recombinant Human Delta-like protein 3(DLL3),partial (Active) (CSB-MP882142HU)
Validated Data
Greater than 71.6% as determined by SDS-PAGE.
Immobilized DLL3 at 2 μg/ml can bind Anti-DLL3 Recombinant Antibody (CSB-RA882142A1HU), the EC50 is 1.102-1.707 ng/mL.
The following DLL3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
DLL3 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA882142LA01HU | DLL3 Antibody |
Human | ELISA, IHC |
| CSB-PA882142LB01HU | DLL3 Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA882142LC01HU | DLL3 Antibody, FITC conjugated |
Human | |
| CSB-PA882142LD01HU | DLL3 Antibody, Biotin conjugated |
Human | ELISA |
| CSB-RA882142A1HU | DLL3 Monoclonal Antibody |
Human | ELISA, FC |
DLL3 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP346574XBE CSB-EP346574XBE CSB-BP346574XBE CSB-MP346574XBE CSB-EP346574XBE-B |
Recombinant Xenopus laevis Homeobox protein DLL-3(dll3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL3 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP882142HU | Recombinant Human Delta-like protein 3(DLL3),partial |
Yeast |
| CSB-EP882142HU | Recombinant Human Delta-like protein 3(DLL3),partial |
E.coli |
| CSB-BP882142HU CSB-MP882142HU CSB-EP882142HU-B |
Recombinant Human Delta-like protein 3(DLL3)，partial |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP882142HU1 | Recombinant Human Delta-like protein 3(DLL3),partial |
E.coli |
| CSB-MP882142HU | Recombinant Human Delta-like protein 3(DLL3),partial (Active) |
Mammalian cell |
DLL3 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF006948RA | Recombinant Rat Delta-like protein 3(Dll3) |
in vitro E.coli expression system |
| CSB-YP006948RA1 CSB-EP006948RA1 CSB-BP006948RA1 CSB-MP006948RA1 CSB-EP006948RA1-B |
Recombinant Rat Delta-like protein 3(Dll3),partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL3 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF006948MO | Recombinant Mouse Delta-like protein 3(Dll3) |
in vitro E.coli expression system |
| CSB-YP006948MO1 CSB-EP006948MO1 CSB-BP006948MO1 CSB-MP006948MO1 CSB-EP006948MO1-B |
Recombinant Mouse Delta-like protein 3(Dll3),partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL3 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL006948HU | Human Delta-like protein 3(DLL3) ELISA kit |
serum, plasma, tissue homogenates | 4.68 pg/mL |
