Recombinant Mouse Lymphotactin protein(Xcl1) (Active)

In Stock
Code CSB-AP001201MO
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P47993
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias C motif chemokine 1, Lymphotaxin, Small-inducible cytokine C1
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100 ng/ml, corresponding to a specific activity of >1.0x104 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Research Area Immunology
Source E.coli
Gene Names Xcl1
Expression Region 22-114aa
Tag Info Tag-Free
Mol. Weight 10.1 kDa
Protein Description Full Length of Mature Protein
PubMed ID 7973732; 7875320; 9199871; 15489334
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Function Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Subcellular Location Secreted
Protein Families Intercrine gamma family
Tissue Specificity Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells.
Database Links

KEGG: mmu:16963

STRING: 10090.ENSMUSP00000027860

UniGene: Mm.190

Pathway Chemokine signaling pathway

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