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The recombinant FOS monoclonal antibody is produced using in vitro expression system. The expression system is constructed by cloning the human FOS DNA sequence into the expression vector and transfecting clones into the cell line. Individual clones are screened to select the best candidates for production. This FOS antibody shows reactivity with FOS protein from human and mouse. It has undergone affinity-chromatography purification. And it has been tested quality in ELISA, WB, IHC, IF, FC applications.
c-Fos binds to c-Jun to form activator protein 1 (AP1), one of the most powerful transcriptional factors of the immune system. In addition to playing a role in immune regulation, c-Fos is also involved in inflammation and apoptosis.
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