Rat Interleukin 6,IL-6 ELISA KIT

Code CSB-E04640r
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P20607
Lead Time 3-5 working days
Abbreviation IL6
Protein Biological Process 1 Immunity
Target Name interleukin 6 (interferon, beta 2)
Alias BSF2, HGF, HSF, IFNB2, IL-6, B cell stimulatory factor-2|B-cell differentiation factor|CTL differentiation factor|OTTHUMP00000158544|hybridoma growth factor|interleukin 6|interleukin BSF-2
Species Rattus norvegicus (Rat)
Protein Biological Process 3 Acute phase
Sample Types serum, plasma, tissue homogenates
Detection Range 0.312 pg/mL-20 pg/mL
Sensitivity 0.078 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Immunology
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
HGNC 1834
RGD 2327
MGI 88373
References
Still Have Questions? Leave a Message or Start an on-line Chat
Function Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation (By similarity).
Subcellular Location Secreted
Protein Families IL-6 superfamily
Database Links

KEGG: rno:24498

STRING: 10116.ENSRNOP00000013732

UniGene: Rn.9873

Pathway HIF-1 signaling pathway
Jak-STAT signaling pathway
PI3K-Akt signaling pathway
TNF signaling pathway
Cellular senescence
Hematopoietic cell lineage
IL-17 signaling pathway
NOD-like receptor signaling pathway
Th17 cell differentiation
Toll-like receptor signaling pathway
AGE-RAGE signaling pathway in diabetic complications
FoxO signaling pathway
Inflammatory Pain

Q&A and Customer Reviews

Q&A
Q:

Seeking quotation for ELISA kits of IL-6. I am working on SD Rats and project related to High Fat Diet induced Metabolic complications.

A:
Thanks for your inquiry.
We have this kit available:
#CSB-E04640r,Rat Interleukin 6,IL-6 ELISA KIT
Usually this kit is used to test commmon rats, but it can also detect SD Rats.Pls follow your actual test result. I will send you the kit manual by email and ask the local distributor to give you a quote soon.
Q:

Seeking for ELISA kits of rat IL-6 .I am working on SD Rats and project related to High Fat Diet induced Metabolic complications.

A:
Thanks for your inquiry.
For the mentiond detection targets,we have the following kit:
#CSB-E04640r,Rat Interleukin 6,IL-6 ELISA KIT
And we use kits to test ordinary rats.While there is not big problems to detect SD Rats.Pls take your actual test results as the real results.
Customer Reviews
  • Tested application: ELISA
    Test sample: Serum,Tissue homogenate: heart tissue homogenate
    Species: Rat
    Review: The standard was worked perfectly in my experiment but I could don get much difference in control and disease group animal serum samples.

Related Products

Il6 Proteins

Il6 Proteins for Rattus norvegicus (Rat)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.