HMGB1 Research Reagents

High mobility group protein B1 is a protein in humans that is encoded by HMGB1 gene. Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as danger associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury

The following HMGB1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

HMGB1 Antibody

HMGB1 Protein

HMGB1 ELISA Kit

HMGB1 Antibodies

HMGB1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA01604A0Rb	HMGB1 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA01604B0Rb	HMGB1 Antibody, HRP conjugated	Human	ELISA
CSB-PA01604C0Rb	HMGB1 Antibody, FITC conjugated	Human
CSB-PA01604D0Rb	HMGB1 Antibody, Biotin conjugated	Human	ELISA
CSB-PA010553GA01HU	HMGB1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA049959	HMGB1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA000149	Acetyl-HMGB1 (K12) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA002937	HMGB1 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA005927	HMGB1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA995991	HMGB1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA225274	HMGB1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA010553YA01HU	HMGB1 Antibody	Human, Mouse	ELISA, WB, IHC, IF
CSB-PA010553YB01HU	HMGB1 Antibody, HRP conjugated	Human	ELISA
CSB-PA010553YC01HU	HMGB1 Antibody, FITC conjugated	Human
CSB-PA010553YD01HU	HMGB1 Antibody, Biotin conjugated	Human	ELISA
CSB-RA439052A0HU	HMGB1 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC

HMGB1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA523735XA01DOA	HMGB1 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

HMGB1 Antibodies for Gallus gallus (Chicken)

Code	Product Name	Species Reactivity	Application
CSB-PA590934XA01CH	HMGB1 Antibody	Gallus gallus (Chicken)	ELISA, WB (ensure identification of antigen)

HMGB1 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA010553NA01RA	Hmgb1 Antibody	Rat	ELISA, WB
CSB-PA010553NB01RA	Hmgb1 Antibody, HRP conjugated	Rat	ELISA
CSB-PA010553NC01RA	Hmgb1 Antibody, FITC conjugated	Rat
CSB-PA010553ND01RA	Hmgb1 Antibody, Biotin conjugated	Rat	ELISA
CSB-PA010553NA01MO	Hmgb1 Antibody	Rat	ELISA, WB

HMGB1 Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA010553ZA01MO	Hmgb1 Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

HMGB1 Proteins

HMGB1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP010553BO CSB-EP010553BO CSB-BP010553BO CSB-MP010553BO CSB-EP010553BO-B	Recombinant Bovine High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP010553PI CSB-EP010553PI CSB-BP010553PI CSB-MP010553PI CSB-EP010553PI-B	Recombinant Pig High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-BP010553MO CSB-MP010553MO CSB-EP010553MO-B	Recombinant Mouse High mobility group protein B1(Hmgb1)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP010553MO	Recombinant Mouse High mobility group protein B1(Hmgb1)	E.coli

HMGB1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-BP010553RA CSB-MP010553RA CSB-EP010553RA-B	Recombinant Rat High mobility group protein B1(Hmgb1)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP010553RA	Recombinant Rat High mobility group protein B1(Hmgb1)	E.coli
CSB-YP010553RA	Recombinant Rat High mobility group protein B1(Hmgb1)	Yeast
CSB-YP010553RAa1	Recombinant Rat High mobility group protein B1(Hmgb1)	Yeast

HMGB1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP010553HU	Recombinant Human High mobility group protein B1(HMGB1),partial	Yeast
CSB-EP010553HU CSB-BP010553HU CSB-EP010553HU-B	Recombinant Human High mobility group protein B1(Hmgb1),partial	E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-RP016044h	Recombinant Human High mobility group protein B1(HMGB1),partial	E.coli

HMGB1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Code	Product Name	Source
CSB-YP362058DXU CSB-EP362058DXU CSB-BP362058DXU CSB-MP362058DXU CSB-EP362058DXU-B	Recombinant Cricetulus griseus High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Papio anubis (Olive baboon)

Code	Product Name	Source
CSB-YP434996ERI CSB-EP434996ERI CSB-BP434996ERI CSB-MP434996ERI CSB-EP434996ERI-B	Recombinant Papio anubis High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP523735DOA CSB-EP523735DOA CSB-BP523735DOA CSB-MP523735DOA CSB-EP523735DOA-B	Recombinant Arabidopsis thaliana High mobility group B protein 1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

Code	Product Name	Source
CSB-YP533334CYL CSB-EP533334CYL CSB-BP533334CYL CSB-MP533334CYL CSB-EP533334CYL-B	Recombinant Callithrix jacchus High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Plecturocebus moloch (Dusky titi monkey) (Callicebus moloch)

Code	Product Name	Source
CSB-YP541463CYE CSB-EP541463CYE CSB-BP541463CYE CSB-MP541463CYE CSB-EP541463CYE-B	Recombinant Callicebus moloch High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP600961HO CSB-EP600961HO CSB-BP600961HO CSB-MP600961HO CSB-EP600961HO-B	Recombinant Horse High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP703137MOV CSB-EP703137MOV CSB-BP703137MOV CSB-MP703137MOV CSB-EP703137MOV-B	Recombinant Macaca fascicularis High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP751094DO CSB-EP751094DO CSB-BP751094DO CSB-MP751094DO CSB-EP751094DO-B	Recombinant Dog High mobility group protein B1(HMGB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HMGB1 ELISA Kit

HMGB1 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Sample Types	Sensitivity
CSB-EL010553DO	Dog High mobility group protein B1(HMGB1) ELISA kit	serum, plasma, tissue homogenates, cell lysates	0.078 ng/mL

HMGB1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E08223h	Human High mobility group protein B1,HMGB-1 ELISA Kit	serum, plasma, tissue homogenates, cell lysates	19.5 pg/mL

HMGB1 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-E08225m	Mouse High mobility group protein B1,HMGB-1 ELISA Kit	serum, plasma, tissue homogenates, cell lysates	3.9 pg/mL

HMGB1 ELISA Kit for Sus scrofa (Pig)

Code	Product Name	Sample Types	Sensitivity
CSB-EL010553PI	Pig High mobility group protein B1(HMGB1) ELISA kit	serum, plasma, tissue homogenates	0.078 ng/mL

HMGB1 ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-E08224r	Rat High mobility group protein B1,HMGB-1 ELISA Kit	serum, plasma, tissue homogenates

HMGB1 Background

High mobility group protein B1 is a protein in humans that is encoded by the HMGB1 gene. The HMGB1 protein is a multifunctional redox-sensitive protein with various roles in different cellular compartments. In the nucleus, it is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair, and genome stability. And it is proposed to be a universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. HMGB1 acts as danger-associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury

Popular Pathways

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