Interleukin-17A is a protein in humans that is encoded by IL17A gene. Ligand for IL17RA and IL17RC.
The IL17 family is a class of pro-inflammatory cytokines secreted by CD4+T cells, and it consists of six members, including IL17A. ILU17A is located on chromosome 6p12.2 and transmits the signal by Il17R. It can induce the expression of a variety of inflammatory factors, mediate the inflammatory response and accelerate body repair to play a protective role. In chronic inflammation, IL17A continuously promotes the release of cytokines, chemokines, matrix metalloproteinases, and others as well as immune cell infiltration by activating NF-ҠB, JAK/STAT, and other signaling pathways, thereby promoting the occurrence and development of the disease. In addition, IL17A can also promote the secretion of a variety of angiogenic regulatory factors, and promote the formation and metastasis of tumor blood vessels.
Recombinant Human Interleukin-17A(IL17A)(T26A) (Active) CSB-BP624104HU(M)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Measured by its binding ability in a functional ELISA. Immobilized Human IL17A at 2 μg/ml can bind Anti-IL17A recombinant antibody (CSB-RA624104MA1HU), the EC50 is 1.818-2.170 ng/mL.
The following IL17A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IL17A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA011597GA01HU | IL17A Antibody |
Human | ELISA,IHC |
CSB-PA06659A0Rb | IL17A Antibody |
Human | ELISA, IHC, IF |
CSB-PA06659B0Rb | IL17A Antibody, HRP conjugated |
Human | ELISA |
CSB-PA06659C0Rb | IL17A Antibody, FITC conjugated |
Human | |
CSB-PA06659D0Rb | IL17A Antibody, Biotin conjugated |
Human | ELISA |
IL17A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP624104HU CSB-EP624104HU CSB-BP624104HU CSB-MP624104HU CSB-EP624104HU-B |
Recombinant Human Interleukin-17A(IL17A) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP001851HU | Recombinant Human Interleukin-17A protein(IL17A) |
E.Coli |
CSB-AP004331HU | Recombinant Human Interleukin-17A(IL17A) (Active) |
E.coli |
CSB-AP004341HU | Recombinant Human Interleukin-17A(IL17A) (Active) |
Mammalian cell |
CSB-AP004701HU | Recombinant Human IL17A & IL17F Heterodimer Protein (Active) |
Mammalian cell |
IL17A Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP717213RA CSB-BP717213RA CSB-MP717213RA CSB-EP717213RA-B |
Recombinant Rat Interleukin-17A(Il17a) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP720298MO CSB-EP720298MO CSB-BP720298MO CSB-MP720298MO CSB-EP720298MO-B |
Recombinant Mouse Interleukin-17A(Il17a) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP004781MO | Recombinant Mouse Interleukin-17A(Il17a),partial (Active) |
Mammalian cell |
IL17A Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP724243BO CSB-EP724243BO CSB-BP724243BO CSB-MP724243BO CSB-EP724243BO-B |
Recombinant Bovine Interleukin-17A(IL17A) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP736792PI CSB-BP736792PI CSB-MP736792PI CSB-EP736792PI-B |
Recombinant Pig Interleukin-17A(IL17A) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL17A ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04608m | Mouse Interleukin 17,IL-17 ELISA Kit |
serum, plasma, tissue homogenates | 19.5 pg/ml |
IL17A ELISA Kit for Sus scrofa (Pig)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08057p | Pig interleukin 17,IL-17 ELISA Kit |
serum, plasma, tissue homogenates | 10 pg/mL |
IL17A ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E07451r | Rat Interleukin 17,IL-17 ELISA KIT |
serum, plasma, tissue homogenates | 23.43 pg/mL |
IL17A ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E12819h | Human Interleukin 17A (IL-17A/IL-17) ELISA Kit |
serum, plasma, tissue homogenates | 15.6 pg/ml |