Osteoporosis - The Silent Health Killer

World Osteoporosis Day

World Osteoporosis Day is celebrated on 20 October each year and was officially established by the World Health Organisation (WHO) in 1998, with the aim of spreading awareness of osteoporosis and preventing and reducing the incidence of osteoporotic fractures. 2024 World Osteoporosis Day is themed ‘Say no to fragile bones’, encouraging people of all ages to pay attention to and protect their bone health.

Osteoporosis is a systemic bone disease caused by a variety of factors, mainly characterised by a decrease in bone density and quality, and damage to the bone microstructure, resulting in an increase in bone fragility and an increased susceptibility to fracture. Osteoporosis is mainly classified into two categories: primary and secondary. Primary osteoporosis is subdivided into postmenopausal osteoporosis (type I), senile osteoporosis (type II) and idiopathic osteoporosis. Osteoporosis is closely related to sarcopenia and the two often occur together, increasing the risk of falls and fractures.

The causes of osteoporosis are complex and varied, including genetic factors, changes in hormone levels, lifestyle habits and the effects of disease. According to statistics, there are currently about 200 million osteoporosis patients worldwide, and among people over 50 years old, the prevalence of osteoporosis in women is about 33%, while that in men is about 20%. With aging becoming more and more serious, the prevalence of osteoporosis tends to increase year by year. Therefore, it is crucial to raise the awareness of osteoporosis and strengthen the research and prevention of osteoporosis.

CUSABIO has long been committed to providing researchers with high-quality proteins, antibodies, ELISA kits and other tools for scientific research reagents, and has compiled a series of popular targets related to osteoporosis research and related reagent products listed below for your selection:

● Recombinant Proteins Relevant to Osteoporosis Research

Target Product Name Source Tag Info Product Code
ACP5 Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5) Yeast C-terminal 6xHis-tagged CSB-YP001178HU
ALPP Recombinant Human Alkaline phosphatase, placental type (ALPP), partial Baculovirus N-terminal 10xHis-tagged CSB-BP001632HU1
ALPP Recombinant Human Alkaline phosphatase, placental type (ALPP), partial E.coli N-terminal 10xHis-tagged CSB-EP001632HU1
BGLAP Recombinant Chicken Osteocalcin (BGLAP) E.coli N-terminal 6xHis-KSI-tagged CSB-EP002682CH
BGLAP Recombinant Dog Osteocalcin (BGLAP) E.coli N-terminal 6xHis-KSI-tagged CSB-EP002682DO
Bglap Recombinant Mouse Osteocalcin (Bglap) E.coli N-terminal 6xHis-SUMO-tagged CSB-EP002682MO
Bglap Recombinant Rat Osteocalcin (Bglap) E.coli N-terminal GST-tagged CSB-EP002682RA
CTNNB1 Recombinant Human Catenin beta-1 (CTNNB1) E.coli N-terminal GST-tagged CSB-EP006169HU
CTNNB1 Recombinant Human Catenin beta-1 (CTNNB1) Yeast N-terminal 6xHis-tagged CSB-YP006169HU
CTNNB1 Recombinant Human Catenin beta-1 (CTNNB1) E.coli N-terminal 6xHis-tagged CSB-EP006169HUa0
CTSK Recombinant Dog Cathepsin K (CTSK) E.coli N-terminal 6xHis-SUMO-tagged CSB-EP006192DO
CTSK Recombinant Human Cathepsin K (CTSK) E.coli N-terminal 6xHis-tagged CSB-EP006192HU
Ctsk Recombinant Mouse Cathepsin K (Ctsk) E.coli N-terminal 6xHis-tagged CSB-EP006192MO
CTSK Recombinant Macaca fascicularis Cathepsin K (CTSK) E.coli N-terminal 6xHis-tagged CSB-EP006192MOV
Ctsk Recombinant Rat Cathepsin K (Ctsk) E.coli N-terminal 6xHis-tagged CSB-EP006192RA
Ctsk Recombinant Rabbit Cathepsin K (Ctsk) E.coli N-terminal 6xHis-tagged CSB-EP006192RB
CTSK Recombinant Human Cathepsin K (CTSK) Yeast N-terminal 6xHis-tagged CSB-YP006192HU
CTSK Recombinant Vaccinia virus Protein K3 (VACWR034) Baculovirus N-terminal 6xHis-tagged CSB-BP323585VAI
ESR1 Recombinant Human Estrogen receptor (ESR1), partial Yeast N-terminal 6xHis-tagged CSB-YP007830HU
Esr1 Recombinant Mouse Estrogen receptor (Esr1), Biotinylated E.coli N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged CSB-EP007830MO-B

● Antibodies Relevant to Osteoporosis Research

CSB-MA004888A0m IF

CD19 Monoclonal Antibody
CSB-MA004888A0m

Tested Applications: ELISA, WB, IHC, IF, FC

CSB-RA004936MA1HU FC

CD40 Recombinant Monoclonal Antibody
CSB-RA004936MA1HU

Tested Applications: ELISA, IF, FC

CSB-RA246383A0HU IP

CD80 Recombinant Monoclonal Antibody
CSB-RA246383A0HU

Tested Applications: ELISA, WB, IHC, IP

CSB-RA011931A100phHU IHC

Phospho-JAK2 (Y1007 + Y1008) Recombinant Monoclonal Antibody
CSB-RA011931A100phHU

Tested Applications: ELISA, WB, IHC, IP

Antibody Type Product Name Species Reactivity Tested Applications Code
Polyclonal Antibody BTK Antibody Human, Mouse ELISA, WB, IHC, IF CSB-PA002867LA01HU
Polyclonal Antibody Phospho-BTK (Y223) Antibody Human, Mouse, Rat ELISA, WB CSB-PA000638
Polyclonal Antibody BTK Antibody Human, Mouse, Rat ELISA, WB CSB-PA005537
Polyclonal Antibody Phospho-BTK (Y551) Antibody Human, Mouse, Rat ELISA, WB CSB-PA000639
Polyclonal Antibody BTK Antibody Human, Mouse, Rat, Monkey ELISA, WB, IHC CSB-PA001066
Polyclonal Antibody BTK Antibody Human, Mouse, Rat ELISA, WB CSB-PA002867GA01HU
Polyclonal Antibody Phospho-BTK (Tyr223) Antibody Human, Mouse, Rat ELISA, WB CSB-PA142166
Recombinant Antibody BTK Recombinant Monoclonal Antibody Human ELISA, IHC CSB-RA553167A0HU
Monoclonal Antibody CD19 Monoclonal Antibody Human ELISA, WB, IHC, IF, FC CSB-MA004888A0m
Monoclonal Antibody CD19 Monoclonal Antibody Human ELISA, WB, IHC, FC CSB-MA004888A1m
Monoclonal Antibody CD19 Monoclonal Antibody,APC Conjugated Human ELISA, IF, FC CSB-MA195220
Monoclonal Antibody CD19 Monoclonal Antibody,Biotin Conjugated Human ELISA, IF, FC CSB-MA899608
Monoclonal Antibody CD19 Monoclonal Antibody,FITC Conjugated Human ELISA, IF, FC CSB-MA047662
Monoclonal Antibody CD19 Monoclonal Antibody,PE Conjugated Human ELISA, IF, FC CSB-MA036486
Monoclonal Antibody CD19 Monoclonal Antibody,PE-Cy5 Conjugated Human ELISA, IF, FC CSB-MA281869
Monoclonal Antibody CD19 Monoclonal Antibody,Purified Human ELISA, FC CSB-MA798261
Polyclonal Antibody CD19 Antibody Human, Mouse, Monkey ELISA, WB CSB-PA001431
Polyclonal Antibody Phospho-CD19 (Y531) Antibody Human, Mouse, Monkey ELISA, WB CSB-PA070286
Polyclonal Antibody CD19 Antibody Human ELISA, WB CSB-PA006159
Polyclonal Antibody CD19 (Ab-531) Antibody Human, Mouse ELISA, WB CSB-PA253616

● ELISA Kits Relevant to Osteoporosis Research

CSB-E04640r standard curves

Rat TNF-α ELISA kit
CSB-E04640r

337 Citations

CSB-E05071m standard curves

Mouse INS ELISA Kit
CSB-E05071m

117 Citations

CSB-E11987r standard curves

Rat TNF-α ELISA kit
CSB-E11987r

455 Citations

CSB-E04741m standard curves

Mouse TNF-α ELISA KIT
CSB-E04741m

381 Citations

Target Product Name Sample Types Detection Range Code
IL6 Human Interleukin 6,IL-6 ELISA KIT serum, plasma, cell culture supernates, tissue homogenates, urine 7.8 pg/mL-500 pg/mL CSB-E04638h
IL6 Mouse Interleukin 6,IL-6 ELISA KIT Request Information CSB-E04639m
IL6 Rat Interleukin 6,IL-6 ELISA KIT Request Information CSB-E04640r
INS Rat Insulin,INS ELISA KIT serum, plasma, cell culture supernates 15.6 nIU/mL-1000 nIU/mL CSB-E05070r
INS Mouse Insulin,INS ELISA KIT serum, plasma, cell culture supernates, tissue homogenates, cell lysates 15.6 nIU/mL-1000 nIU/mL CSB-E05071m
NFKB1 Rat Nuclear factor-kappa B(NF-κB) ELISA KIT serum, plasma, tissue homogenates 1.56 pg/mL-100 pg/mL CSB-E13148r
TNF Human Tumor necrosis factor α,TNF-α ELISA KIT serum, plasma, cell culture supernates, tissue homogenates, cell lysates 7.8 pg/mL-500 pg/mL CSB-E04740h
TNF Mouse Tumor necrosis factor α,TNF-α ELISA KIT serum, plasma, cell culture supernates, tissue homogenates 15.6 pg/ml-1000 pg/ml CSB-E04741m
TNF Rat TNF-α ELISA KIT serum, plasma, cell culture supernates, tissue homogenates 6.25 pg/mL-400 pg/mL CSB-E11987r
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