Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Nef(nef)

Product Type Recombinant Protein
Uniprot No. P20867
Species Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
Gene Names nef
Protein Names Recommended name: Protein Nef Alternative name(s): 3'ORF Negative factor Short name= F-protein Cleaved into the following chain: 1. C-terminal core protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Factor of infectivity and pathogenicity, required for optimal virus replication. Alters numerous pathways of T-lymphocytes function and down-regulates immunity surface molecules in order to evade host defense and increase viral infectivity. Alters the functionality of other immunity cells, like dendritic cells, monocytes/macrophages and NK cells.
Subcellular Location Host cell membrane, Lipid-anchor, Cytoplasmic side, Virion, Secreted, Host Golgi apparatus membrane
Protein Families Lentivirus primate group Nef protein family

Product Details for Different Expression Systems

Product Name Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Nef(nef),Yeast
Code CSB-YP322697HKS
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence GGKWSKHSV PGWSTVRERM RRAEPATDRV RQTEPAAVGV GAVSRDLEKH GAITSSNTAA TNADCAWLEA YEDEEVGFPV RPQVPLRPMT YKAAIDLSHF LKEKGGLEGL IYSQKRQDIL DLWIYHTQGY FPDWQNYTAG PGVRFPLTFG WCFKLVPVDP EKVEEANEGE NNCLLHPMSQ HGMDDPEKEV LVWKFDSKLA LHHVARELHP EYYKDC
Expression Region 2-216
Protein Description Full Length of Mature Protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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Product Name Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Nef(nef),E.coli
Code CSB-EP322697HKS
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence GGKWSKHSV PGWSTVRERM RRAEPATDRV RQTEPAAVGV GAVSRDLEKH GAITSSNTAA TNADCAWLEA YEDEEVGFPV RPQVPLRPMT YKAAIDLSHF LKEKGGLEGL IYSQKRQDIL DLWIYHTQGY FPDWQNYTAG PGVRFPLTFG WCFKLVPVDP EKVEEANEGE NNCLLHPMSQ HGMDDPEKEV LVWKFDSKLA LHHVARELHP EYYKDC
Expression Region 2-216
Protein Description Full Length of Mature Protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Nef(nef),Baculovirus
Code CSB-BP322697HKS
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence GGKWSKHSV PGWSTVRERM RRAEPATDRV RQTEPAAVGV GAVSRDLEKH GAITSSNTAA TNADCAWLEA YEDEEVGFPV RPQVPLRPMT YKAAIDLSHF LKEKGGLEGL IYSQKRQDIL DLWIYHTQGY FPDWQNYTAG PGVRFPLTFG WCFKLVPVDP EKVEEANEGE NNCLLHPMSQ HGMDDPEKEV LVWKFDSKLA LHHVARELHP EYYKDC
Expression Region 2-216
Protein Description Full Length of Mature Protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Nef(nef),Mammalian cell
Code CSB-MP322697HKS
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence GGKWSKHSV PGWSTVRERM RRAEPATDRV RQTEPAAVGV GAVSRDLEKH GAITSSNTAA TNADCAWLEA YEDEEVGFPV RPQVPLRPMT YKAAIDLSHF LKEKGGLEGL IYSQKRQDIL DLWIYHTQGY FPDWQNYTAG PGVRFPLTFG WCFKLVPVDP EKVEEANEGE NNCLLHPMSQ HGMDDPEKEV LVWKFDSKLA LHHVARELHP EYYKDC
Expression Region 2-216
Protein Description Full Length of Mature Protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat

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