Growth Factor ELISA Kits

Growth factors are a class of secreted proteins or peptides that act as biologically active substances capable of promoting cell growth, proliferation, and differentiation. They are widely present in various tissues and organs of the human body and play important roles in physiological and pathological processes such as embryonic development, tissue repair, immune regulation, hematopoiesis, neural development, and tumor growth.

Classification and biological functions of growth factors

There are many kinds of growth factors, mainly including:

  • Basic Fibroblast Growth Factors (bFGFs): for example, FGF-2 is involved in cell proliferation, angiogenesis and tissue repair.
  • Epidermal Growth Factors (EGFs): for example, EGF and TGF-α play a key role in the proliferation, differentiation and repair of epithelial cells.
  • Nerve Growth Factors (NGFs): for example, NGF and BDNF regulate the growth, survival and junction formation of neurons.
  • Platelet-Derived Growth Factors (PDGFs): such as PDGF-A and PDGF-B, are involved in angiogenesis, cell proliferation and tissue repair.
  • Interleukins (ILs): such as IL-1, have pro-inflammatory effects and play a role in the body's response to infection and inflammation.
  • Tumor Necrosis Factors (TNFs): such as TNF-α, regulate immune regulation, inflammatory response, and apoptosis.
  • Insulin-like Growth Factors (IGFs): for example, IGF-1 and IGF-2, and they are involved in cell growth, metabolism and differentiation.
  • Vascular Endothelial Growth Factors (VEGFs): such as VEGF-A and VEGF-B, regulate angiogenesis and vascular permeability.
  • Transforming Growth Factors (TGFs): such as TGF-β and BMPs, have regulatory effects on cell proliferation, differentiation and matrix synthesis.

Growth factor and diseases

  • Tumors: EGFR and VEGF, among others, can promote tumor cell proliferation, angiogenesis, and metastasis, influencing the malignancy and prognosis of tumors.
  • Cardiovascular disease: IGF and FGF can promote myocardial cell proliferation and angiogenesis, which are of significant importance in the treatment of cardiovascular diseases and myocardial regeneration.
  • Nervous system diseases: NGF and Brain-Derived Neurotrophic Factor (BDNF), among other growth factors, hold promising potential for the treatment of neurological disorders such as Alzheimer's disease, Parkinson's disease, and more.
  • Inflammatory diseases: TNF and interleukin (IL) are involved in the regulation of the inflammatory response. They play an important role in the activation of immune cells, the release of inflammatory mediators and the repair of tissue damage, and are related to inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.
  • Metabolic diseases: Insulin and IGF are key factors for regulating blood glucose and energy metabolism. They play an important role in the occurrence and progression of metabolic diseases such as diabetes and obesity.

Growth factor related ELISA kits

As a type of cytokine with important biological functions and pharmaceutical research value, growth factor ELISA kit products provided by CUSABIO covers almost all growth factor types, and all products have high sensitivity, high precision and high stability. Below are some display images of growth factor ELISA kits provided by CUSABIO.

Code Product Name Sensitivity Detection Range
CSB-EL003433MO Mouse myeloid-derived growth factor precursor (C19orf10) ELISA kit 3.9 pg/mL 15.6 pg/mL-1000 pg/mL
CSB-E13386c Canine connective tissue growth factor,CTGF ELISA Kit 15.6 pg/mL 62.5 pg/mL-4000 pg/mL
CSB-E07875h Human connective tissue growth factor (CTGF) ELISA kit 1.875 pg/mL 3.75 pg/mL-120 pg/mL
CSB-E07877m Mouse connective tissue growth factor,CTGF ELISA Kit 0.195 pg/mL 0.78 pg/mL-50 pg/mL
CSB-E07876r Rat connective tissue growth factor,CTGF ELISA Kit 0.039 ng/mL 0.156 ng/mL-10 ng/mL
CSB-E08027h Human Epidermal growth factor,EGF ELISA Kit 0.39 pg/mL 1.56 pg/mL-100 pg/mL
CSB-E08028m Mouse Epidermal growth factor,EGF ELISA Kit 1.95 pg/mL 7.8 pg/mL-500 pg/mL
CSB-E17171B Bovine Epithelial growth factor(EGF)ELISA Kit 0.039 ng/mL 0.156 ng/mL-10 ng/mL
CSB-E09868Ch Chicken Epidermal growth factor,EGF ELISA Kit 31.25 pg/mL 125 pg/mL-8000 pg/mL
CSB-E06788p Pig Epithelial growth factor,EGF ELISA Kit 125 pg/mL 250 pg/mL-10000 pg/mL
CSB-E06909Rb Rabbit Epidermal growth factor,EGF ELISA Kit 0.25 ng/mL 0.5 ng/mL-8 ng/mL
CSB-E08029r Rat Epidermal growth factor,EGF ELISA Kit 0.78 pg/mL 3.12 pg/mL-200 pg/mL
CSB-EL007475HU Human Epidermal growth factor-like protein 6(EGFL6) ELISA kit 19.5 pg/mL 78 pg/mL-5000 pg/mL
CSB-EL007475MO Mouse Epidermal growth factor-like protein 6(EGFL6) ELISA kit 23.43 pg/mL 93.75 pg/mL-6000 pg/mL
CSB-E15864h Human Epidermal growth factor Like Domain Protein, Multiple 7 (EGFL7) ELISA Kit 0.12 μg/mL 0.47 μg/mL-30 μg/mL
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