Inflammatory Cytokine ELISA Kits

Inflammatory cytokines refer to the cytokines that regulate various inflammatory responses, including pro-inflammatory cytokines and anti-inflammatory cytokines. The balance between pro-inflammatory and anti-inflammatory cytokines is crucial for maintaining the normal function of the immune system and tissue repair.

Pro-inflammatory cytokines

The pro-inflammatory cytokines are mainly produced by Th1 cells, CD4+ cells, macrophages, and dendritic cells, and they play a role in upregulating the inflammatory response. The most common pro-inflammatory cytokines include IL-1β, IL-6, IL-8, IL-12, IL-18, TNF-α, and IFN-γ. These cytokines, during infections, tissue damage, and other pathological stimuli, act to activate and recruit other immune cells, helping the body mount an appropriate response to foreign pathogens and injuries.

Anti-inflammatory cytokines

The main function of anti-inflammatory cytokines is to inhibit the inflammatory process, balance the immune response, and prevent excessive inflammation that can lead to tissue damage and disease progression. The primary anti-inflammatory cytokines include IL-1 receptor antagonist (IL-1ra), IL-4, and IL-10. It is important to note that INF-α, TGF-β, IL-6, IL-11 can act as either anti-inflammatory or pro-inflammatory cytokines depending on the cell type and the environment.

Functional characteristics of some inflammatory cytokines

Cytokine Property Receptor Major functions
IL-1ra Anti-inflammatory cytokine IL-1R1 (CD121a) Inhibit IL-1 activity
IL-1β Pro-inflammatory cytokine IL-1R1 (CD121a) Pyrogenic, pro-inflammatory, enhance proliferation and differentiation
IL-4 Anti-inflammatory cytokine IL4R (CD124) Proliferation of B and cytotoxic T cells, enhances MHC class II expression, stimulates IgG and IgE production
IL-6 Pro-inflammatory cytokine IL-6R (CD126), IL6ST (CD130) Induce acute phase protein synthesis, pyrogenic
IL-8 Pro-inflammatory cytokine IL-8R Attract and activate neutrophils
IL-10 Anti-inflammatory cytokine IL10R (CDw210) Inhibit macrophage activity and cytokine production
IL-11 Pro/Anti-inflammatory cytokine IL-11Ra, IL6ST (CD130) Promote differentiation, induce acute phase protein synthesis
IL-12 Pro-inflammatory cytokine IL12RB1 (CD212) Activate NK cells, phagocyte cell activation, endotoxic shock, tumor cytotoxicity, cachexia
IL-13 Pro/anti-inflammatory cytokine IL-13Rα1, IL-13Rα2 Promote B cell proliferation, induce monocyte differentiation, enhance MHC class II expression
IL-18 Pro-inflammatory cytokine IL-18Ra (CD218a) Recruit monocytes and T lymphocytes, synergist with IL-12 in the induction of IFN- γ production and inhibition of angiogenesis
INF-α Pro/anti-inflammatory cytokine IFNAR1, IFNAR2 Anti-viral, cell proliferation suppression
TNF-α Pro-inflammatory cytokine TNFR1, TNFR2 Pyrogenic, phagocyte cell activation, endotoxic shock
TGF-β Pro/Anti-inflammatory cytokine TGF-βR1, 2, 3 Inhibit B cell proliferation, inhibit hematopoiesis, promote wound healing

Inflammatory cytokine related ELISA kits

CUSABIO provides high quality and high sensitivity inflammatory cytokine ELISA kits, which are widely used in the study of inflammatory process and immune response, providing reliable detection results for quantitative determination of inflammatory cytokine levels, helping to reveal the mechanism of immune and inflammatory response, and helping to develop drugs for immune diseases or inflammatory diseases.

Target Code Product Name Sensitivity
AIF1 CSB-EL001490MO Mouse Allograft inflammatory factor 1(AIF1) ELISA kit 1.10 ng/ml
AIF1 CSB-EL001490HU Human Allograft inflammatory factor 1(AIF1) ELISA kit 1.9 ng/mL
CC16 CSB-E08681r Rat Clara cell protein,CC16 ELISA Kit 0.78 pg/mL
CCL11 CSB-E04533h Human eosinophil chemotactic factor,ECF ELISA Kit 7.8 pg/mL
CCL17 CSB-E09257h Human thymus activation regulated chemokine,TARC ELISA Kit 3.9 pg/mL
CCL17 CSB-EL004780RH Monkey C-C motif chemokine 17(CCL17) ELISA kit 9.8 pg/mL
CCL2 CSB-E04655h Human monocyte chemotactic protein 1/monocyte chemotactic and activating factor,MCP-1/MCAF ELISA kit 1.56 pg/ml
CCL2 CSB-E07430m Mouse monocyte chemotactic protein 1/monocyte chemotactic and activating factor,MCP-1/MCAF ELISA kit 19.5 pg/mL
CCL2 CSB-EQ004783HU Human high sensitivity C-C motif chemokine 2 (CCL2) ELISA kit 1.56 pg/mL
CCL2 CSB-E07429r Rat monocyte chemotactic protein 1/monocyte chemotactic and activating factor,MCP-1/MCAF ELISA kit 7.8 pg/mL
CCL20 CSB-E04669r Rat macrophage inflammatory protein 3α,MIP-3α ELISA Kit 1.56 pg/mL
CCL20 CSB-E04667h Human Macrophage Inflammatory Protein-3α,MIP-3α ELISA kit 3.9 pg/mL
CCL23 CSB-E07309h Human Myeloid Progenitor Inhibitory Factor 1,MPIF-1 ELISA Kit 9.7 pg/mL
CCL25 CSB-EL004789MO Mouse C-C motif chemokine 25(CCL25) ELISA kit 7.8 pg/mL
CCL26 CSB-EL004790HU Human C-C motif chemokine 26(CCL26) ELISA kit 3.9 pg/mL
CCL3 CSB-E04663m Mouse Macrophage Inflammatory Protein 1α,MIP-1α ELISA kit 5.8 pg/mL
CCL5 CSB-E17375h Human C-C motif chemokine 5 (CCL5/D17S136E/SCYA5) ELISA kit 2.307 pg/mL
CCL7 CSB-E07426m Mouse monocyte chemotactic protein 3,MCP-3 ELISA kit 0.39 pg/mL
CCR2 CSB-E14200h Human CC-Chemokine Receptor 2,CCR2 ELISA Kit 5.86 pg/mL
CRP CSB-E06847Rb Rabbit C-Reactive Protein,CRP ELISA Kit 2 pg/mL
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join Us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2023 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1