World Chagas Disease Day

April 14 is designated as World Chagas Disease Day, aiming to raise awareness about Chagas disease and highlight the importance of early diagnosis, prevention, and treatment. Chagas disease, also known as American trypanosomiasis, is caused by the parasite Trypanosoma cruzi and is primarily transmitted through the bite of the triatomine bug, also called the "kissing bug." Often referred to as a "silent killer," Chagas disease can remain asymptomatic for years, leading to delayed diagnosis in many patients. This delay can result in severe complications, including heart failure, arrhythmias, and enlargement of digestive organs.

The transmission routes of Chagas disease are diverse, including mother-to-child transmission, blood transfusions, organ transplants, and food contamination. Due to its long-term latent nature, many patients are already in the chronic stage when diagnosed, significantly increasing treatment complexity. Therefore, raising awareness about Chagas disease and promoting early screening and intervention are crucial for improving patient outcomes.

CUSABIO is committed to providing high-quality biological reagents for researchers and has specially compiled a range of Chagas disease - related products, including recombinant proteins, antibodies, and ELISA kits. These products are designed to assist researchers in exploring disease mechanisms and accelerating the development of diagnostic and therapeutic solutions.

Recommended Products for Chagas Disease Research:

● Recombinant Proteins

- Trypanosoma cruzi Recombinant Proteins

Target	Product Name	Source	Tag Info	Code
N/A	Recombinant Trypanosoma cruzi Cruzipain	E.coli	N-terminal 10xHis-tagged and C-terminal Myc-tagged	CSB-EP333107TQY
HSP100	Recombinant Trypanosoma cruzi Heat shock protein 100 (HSP100), partial	E.coli	N-terminal 10xHis-tagged and C-terminal Myc-tagged	CSB-EP517681TQY
KMP-11	Recombinant Trypanosoma cruzi Kinetoplastid membrane protein 11 (KMP-11)	E.coli	N-terminal 10xHis-tagged and C-terminal Myc-tagged	CSB-EP880045TQY
TPR	Recombinant Trypanosoma cruzi Trypanothione reductase (TPR)	Yeast	N-terminal 6xHis-tagged	CSB-YP333370TQY

- Chagas Disease - related Recombinant Proteins

Recombinant Human Interleukin-17A (IL17A) (T26A) (Active)

CSB-BP624104HU(M)

Recombinant Human Interleukin-2 (IL2) (Active)

CSB-MP011629HU

Recombinant Human Interleukin-4 (IL4) (Active)

CSB-MP011659HUd7

Recombinant Human Interleukin-6 (IL6) (Active)

CSB-YP011664HU

Target	Product Name	Code	Source	Tag Info
CD4	Recombinant Human T-cell surface glycoprotein CD4 (CD4), partial	CSB-CF004935HU1	in vitro E.coli expression system	N-terminal 6xHis-tagged
Cd4	Recombinant Mesocricetus auratus T-cell surface glycoprotein CD4 (Cd4), partial	CSB-EP4837MRG	E.coli	N-terminal GST-tagged and C-terminal Strep II-tagged
CD8A	Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain (CD8A), partial	CSB-EP004966BO	E.coli	N-terminal 6xHis-SUMO-tagged
CD8A	Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial	CSB-EP004966HU	E.coli	N-terminal 6xHis-SUMO-tagged
CD8A	Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial	CSB-MP004966HU	Mammalian cell	N-terminal 6xHis-Myc-tagged
CD8A	Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain (CD8A), partial	CSB-YP004966BO	Yeast	N-terminal 6xHis-tagged
CD8A	Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial	CSB-YP004966HU	Yeast	N-terminal 6xHis-tagged
CD8A	Recombinant Dog T-cell surface glycoprotein CD8 alpha chain (CD8A), partial	CSB-EP004966DO1	E.coli	N-terminal 10xHis-tagged
Cd8a	Recombinant Mesocricetus auratus T-cell surface glycoprotein CD8 alpha chain (Cd8a), partial	CSB-EP4831MRG1	E.coli	N-terminal 6xHis-tagged and C-terminal Strep II-tagged
GAPDH	Recombinant Chicken Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	CSB-EP009232CH	E.coli	N-terminal 6xHis-tagged
GAPDH	Recombinant Cricetulus griseus Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	CSB-EP009232DXU	E.coli	N-terminal 6xHis-tagged
GAPDH	Recombinant Human Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	CSB-EP009232HU	E.coli	N-terminal 6xHis-SUMO-tagged
GAPDH	Recombinant Human Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), partial	CSB-EP009232HU1	E.coli	N-terminal GST-tagged
GAPDH	Recombinant Chicken Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), partial, Biotinylated	CSB-EP009232CH-B	E.coli	N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged
GAPDH	Recombinant Human Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	CSB-MP009232HU(A4)	Mammalian cell	C-terminal 10xHis-tagged
IFNG	Recombinant Chicken Interferon gamma (IFNG)	CSB-EP011050CH	E.coli	N-terminal GST-tagged
IFNG	Recombinant Human Interferon gamma (IFNG)	CSB-EP011050HU	E.coli	N-terminal 6xHis-tagged
Ifng	Recombinant Mouse Interferon gamma (Ifng), partial	CSB-EP011050MO1	E.coli	N-terminal 6xHis-tagged
IFNG	Recombinant Marmota monax Interferon gamma (IFNG)	CSB-EP011050MQG	E.coli	N-terminal 6xHis-tagged
Ifng	Recombinant Rat Interferon gamma (Ifng)	CSB-EP011050RA	E.coli	N-terminal GST-tagged

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● Antibodies

CD4 Recombinant Monoclonal Antibody
CSB-RA004935A0HU

Tested Applications: ELISA, WB, IHC

CD8A Recombinant Monoclonal Antibody
CSB-RA934881A0HU

Tested Applications: ELISA, WB, IHC, IP

GAPDH Recombinant Monoclonal Antibody
CSB-RA009232MA1HU

Tested Applications: ELISA, WB, IHC

IL1B Recombinant Monoclonal Antibody
CSB-RA011614MA1HU

Tested Applications: ELISA, IHC, FC

- Recombinant Antibody

Target	Product Name	Code	Species Reactivity	Tested Applications
CD4	CD4 Recombinant Monoclonal Antibody	CSB-RA004935A0HU	Human	ELISA, WB, IHC
CD8A	CD8A Recombinant Monoclonal Antibody	CSB-RA934881A0HU	Human	ELISA, WB, IHC, IP
GAPDH	GAPDH Recombinant Monoclonal Antibody	CSB-RA009232A0HU	Human, Mouse	ELISA, WB
GAPDH	GAPDH Recombinant Monoclonal Antibody	CSB-RA009232MA1HU	Human	ELISA, WB, IHC, IF, FC
IL10	IL10 Recombinant Monoclonal Antibody	CSB-RA011580A0HU	Human	ELISA
IL10	IL10 Recombinant Monoclonal Antibody	CSB-RA011580MA1HU	Human	ELISA, IHC
IL12B	IL12B Recombinant Monoclonal Antibody	CSB-RA895985A0HU	Human	ELISA, FC
IL17A	IL17A Recombinant Monoclonal Antibody	CSB-RA624104MA1HU	Human	ELISA
IL1B	IL1B Recombinant Monoclonal Antibody	CSB-RA011614MA1HU	Human	ELISA, IHC, FC
IL4	IL4 Recombinant Monoclonal Antibody	CSB-RA240377A0HU	Human	ELISA, IHC
IL6	IL6 Recombinant Monoclonal Antibody	CSB-RA011664MA1HU	Human	ELISA
IL6	IL6 Recombinant Monoclonal Antibody	CSB-RA011664MA2HU	Human	ELISA, IHC

- Monoclonal Antibody

Target	Product Name	Code	Species Reactivity	Tested Applications
CD4	CD4 Monoclonal Antibody	CSB-MA000228	Human,Mouse,Rat	ELISA, IHC
CD4	CD4 Monoclonal Antibody,APC Conjugated	CSB-MA043428	Human	ELISA, IF, FC
CD4	CD4 Monoclonal Antibody,Biotin Conjugated	CSB-MA981329	Human	ELISA, IF, FC
CD4	CD4 Monoclonal Antibody,FITC Conjugated	CSB-MA124048	Human	ELISA, IF, FC
CD4	CD4 Monoclonal Antibody,PE Conjugated	CSB-MA260243	Human	ELISA, IF, FC
CD4	CD4 Monoclonal Antibody,PE-Cy5 Conjugated	CSB-MA570802	Human	ELISA, IF, FC
CD4	CD4 Monoclonal Antibody,Purified	CSB-MA783233	Human	ELISA, FC
CD4	CD4 Monoclonal Antibody,PE Conjugated	CSB-MA084552	Mouse	ELISA, FC
CD8A	CD8A Monoclonal Antibody,APC Conjugated	CSB-MA255790	Human	ELISA, IF, FC
CD8A	CD8A Monoclonal Antibody,Biotin Conjugated	CSB-MA955671	Human	ELISA, IF, FC
CD8A	CD8A Monoclonal Antibody,FITC Conjugated	CSB-MA919476	Human	ELISA, IF, FC
CD8A	CD8A Monoclonal Antibody,PE Conjugated	CSB-MA574619	Human	ELISA, IF, FC
CD8A	CD8A Monoclonal Antibody,PE-Cy5 Conjugated	CSB-MA985168	Human	ELISA, IF, FC
CD8A	CD8A Monoclonal Antibody,Purified	CSB-MA927984	Human	ELISA, FC
GAPDH	GAPDH Monoclonal Antibody	CSB-MA000071M0m	Human, Rat, Rabbit	ELISA, WB, IHC, IP, IF, FC
GAPDH	GAPDH Monoclonal Antibody	CSB-MA000071M1m	Human, Mouse, Rabbit	ELISA, WB, IHC, IP, IF
GAPDH	GAPDH Monoclonal Antibody	CSB-MA000071M2m	Human, Rat, Rabbit, Mouse	ELISA, WB, IHC, IP, IF
GAPDH	GAPDH Monoclonal Antibody	CSB-MA000184	Human, Rat, Mouse, Monkey, Dog, Chicken, Hamster, Rabbit, Pig, Sheep, Insect, Yeast	ELISA, WB, IHC
GAPDH	GAPDH Monoclonal Antibody	CSB-MA000195	Human, Rat, Mouse, Monkey, Dog, Chicken, Hamster, Rabbit, Pig, Sheep	ELISA, WB
GAPDH	GAPDH Monoclonal Antibody	CSB-MA072309	Human,Pig,Rat,Mouse	ELISA, WB
IFNG	IFNG Monoclonal Antibody	CSB-MA065241A0m	Human	ELISA, IHC
IL1B	IL1B Monoclonal Antibody	CSB-MA065741A0m	Human	ELISA
IL1B	IL1B Monoclonal Antibody	CSB-MA010884	Human	ELISA, WB, IHC, ICC
IL6	IL6 Monoclonal Antibody	CSB-MA067571A0m	Human	ELISA, WB, IHC
NOS2	NOS2 Monoclonal Antibody	CSB-MA015943A0m	Human	ELISA, WB, FC
TNF	TNF Monoclonal Antibody	CSB-MA084771A0m	Bovine	ELISA
TNF	TNF Monoclonal Antibody	CSB-MA080271	Human,Mouse,Rat	ELISA, WB, IHC
TNF	TNF Monoclonal Antibody	CSB-MA080272	Human,Mouse,Rat	ELISA, WB, IHC

- Polyclonal Antibody

Target	Product Name	Code	Species Reactivity	Tested Applications
CD4	CD4 Antibody	CSB-PA004935ESR2HU	Human	ELISA, IHC
CD4	Phospho-CD4 (S433) Antibody	CSB-PA070257	Human, Mouse	ELISA, IHC, IF
CD4	CD4 Antibody	CSB-PA001453	Human, Mouse	ELISA, WB, IHC, IF
CD4	CD4 Antibody	CSB-PA004935GA01HU	Human, Mouse, Rat	ELISA, WB
CD8A	CD8A Antibody	CSB-PA004966LA01HU	Human	ELISA, IHC
CD8A	CD8A Antibody, FITC conjugated	CSB-PA004966LC01HU	Human
CD8A	CD8A Antibody, Biotin conjugated	CSB-PA004966LD01HU	Human	ELISA
GAPDH	GAPDH Antibody	CSB-PA009232HA01CH	Chicken	ELISA
GAPDH	GAPDH Antibody, FITC conjugated	CSB-PA009232HC01CH	Chicken
GAPDH	GAPDH Antibody, Biotin conjugated	CSB-PA009232HD01CH	Chicken	ELISA
GAPDH	GAPDH Antibody	CSB-PA00029A0Rb	Human, Mouse	ELISA, WB, IHC, IF
GAPDH	GAPDH Antibody, HRP conjugated	CSB-PA00029B0Rb	Human	ELISA
GAPDH	GAPDH Antibody, FITC conjugated	CSB-PA00029C0Rb	Human
GAPDH	GAPDH Antibody, Biotin conjugated	CSB-PA00029D0Rb	Human	ELISA
GAPDH	GAPDH Antibody	CSB-PA009232HA01DXU	Cricetulus griseus	ELISA, WB
GAPDH	GAPDH Antibody, HRP conjugated	CSB-PA009232HB01DXU	Cricetulus griseus	ELISA
GAPDH	GAPDH Antibody, FITC conjugated	CSB-PA009232HC01DXU	Cricetulus griseus
GAPDH	GAPDH Antibody, Biotin conjugated	CSB-PA009232HD01DXU	Cricetulus griseus	ELISA
GAPDH	GAPDH Antibody	CSB-PA000351	Human, Mouse, Rat, Rabbit, Chicken, Monkey, Sheep, X	WB, IHC
GAPDH	GAPDH Antibody	CSB-PA000364	Zebrafish	WB

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● ELISA Kits

Mouse interleukin 10,IL-10 ELISA KIT
CSB-E04594m

118 Citations

Human Interleukin 1β,IL-1β ELISA Kit
CSB-E08053h

128 Citations

Human Interleukin 6,IL-6 ELISA KIT
CSB-E04638h

234 Citations

Rat TNF-α ELISA kit
CSB-E11987r

501 Citations

Target	Product Name	Code	Detection Range	Sensitivity
CD4	Rat cluster of differentiation 4,CD4 ELISA Kit	CSB-E12928r	serum, plasma, tissue homogenates	0.78 U/mL-50 U/mL
CD4	Chicken Cluster of Differentiation 4(CD4) ELISA Kit	CSB-E13114C	serum, plasma, tissue homogenates	3.125 ng/mL-800 ng/mL
CD4	Human cluster of differentiation 4,CD4 ELISA Kit	CSB-E08956h	serum, plasma	0.625 ng/mL-40 ng/mL
CD8A	Human Cluster of differentiation 8,CD8 ELISA Kit	CSB-E12707h	serum, plasma, cell culture supernates, tissue homogenates	62.5 U/mL-4000 U/mL
IFNG	Rat Interferon γ,IFN-γ ELISA Kit	CSB-E04579r-IS	serum, plasma, cell culture supernates, tissue homogenates	31.25 pg/mL-2000 pg/mL
IFNG	Pig Interferon γ,IFN-γ ELISA Kit	CSB-E06794p-IS	serum, plasma, tissue homogenates	6.25 pg/mL-400 pg/mL
IFNG	Mouse Interferon γ ,IFN-γ ELISA Kit	CSB-E04578m-IS
IFNG	Mouse Interferon γ,IFN-γ ELISA Kit	CSB-E04578m(1)	serum, plasma, tissue homogenates	0.156 ng/mL-10 ng/mL
IFNG	Human Interferon γ (IFN-γ) ELISA Kit	CSB-E04577h	Cell Culture Supernates	0.312 ng/ml-20 ng/ml
IFNG	Bovine Interferon γ,IFN-γ ELISA Kit	CSB-E09812b	serum, plasma, tissue homogenates	31.25 pg/mL-2000 pg/mL
IFNG	Chicken Interferon γ,IFN-γ ELISA Kit	CSB-E08550Ch	serum, plasma, tissue homogenates	3.125 pg/mL-800 pg/mL
IFNG	Goat Interferon γ,IFN-γ ELISA Kit	CSB-E12966G	serum, plasma, tissue homogenates	7.8 pg/mL-500 pg/mL
IFNG	Mouse Interferon γ,IFN-γ ELISA Kit	CSB-E04578m	serum, plasma, tissue homogenates, cell culture supernates	15.6 pg/mL-1000 pg/mL
IFNG	Rabbit Interferon γ,IFN-γ ELISA Kit	CSB-E06925Rb	serum, plasma, tissue homogenates	62.5 pg/mL-4000 pg/mL
IFNG	Rat Interferon γ,IFN-γ ELISA Kit	CSB-E04579r	serum, plasma, tissue homogenates	0.625 pg/mL-40 pg/mL
IFNG	Sheep Interferon γ,IFN-γ ELISA Kit	CSB-E14018Sh	serum, plasma, tissue homogenates	5 pg/mL-200 pg/mL
IFNG	Dog Interferon γ,IFN-γ ELISA Kit	CSB-E11262c	serum, plasma, tissue homogenates	3.12 pg/mL-200 pg/mL
IFNG	Monkey Interferon γ,IFN-γ ELISA Kit	CSB-E10049Mo	serum, plasma, tissue homogenates	31.25 pg/mL-2000 pg/mL
IFNG	Pig Interferon γ,IFN-γ ELISA Kit	CSB-E06794p	serum, plasma, tissue homogenates	15.6 pg/mL-1000 pg/mL
IFNG	Fish Interferon γ,IFN-γ ELISA Kit	CSB-E12878Fh	serum, plasma, tissue homogenates	20 pg/mL-4000 pg/mL

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