slo Antibody

1. Removal of element 6b from the endogenous slo gene affected the production of functional ethanol tolerance in an ethanol-vapor recovery from sedation assay. PMID: 26992698
2. slowpoke channels are required specifically in motoneurones for maximum firing rates during locomotion. PMID: 26332699
3. SLO2 Channels Are Inhibited by All Divalent Cations That Activate SLO1 K+ Channels PMID: 26823461
4. Slo mutant larvae exhibit alterations in synapse morphology, active zone size and neurotransmission that are similar to dysc mutants. PMID: 25359729
5. Results show using the Drosophila model organism, we demonstrate a central role for the BK-type Ca(2+) -activated K(+) channel gene slo in the production of alcohol withdrawal seizures PMID: 22734584
6. Here we examined the action of docosahexaenoic acid on the Slo1 channel without any auxiliary subunit and sought to elucidate the biophysical mechanism and the molecular determinants of the DHA sensitivity. PMID: 24127525
7. Our work identifies a Drosophila homolog of a deaf-blindness gene as a new component of the circadian output pathway,termed DYSC(dyschronic) whish expressed in major neuronal tracts and regulates expression of SLOWPOKE PMID: 22532808
8. Our work identifies a Drosophila homolog of a deaf-blindness gene as a new component of the circadian output pathway,termed DYSC(dyschronic) whish expressed in major neuronal tracts and regulates expression of SLOWPOKE (SLO) PMID: 22532808
9. Involved with Slob protein in the circadian regulation of rhythmic locomotor behavior PMID: 12417656
10. the slowpoke channel must be involved in triggering or producing a homeostatic mechanism that opposes the sedative effects of ethanol. PMID: 16269907
11. The Drosophila slowpoke gene includes 14 alternative exons distributed among five sites of alternative splicing. Slowpoke transcripts undergo tissue- and developmental-specific splicing in Drosophila and some exons are diagnostic for specific tissues. PMID: 16716202
12. These results implicate distinct calcium-dependent and -independent mechanisms in the modulation of dSlo by Slob PMID: 17074977

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KEGG: dme:Dmel_CG10693

UniGene: Dm.19520