IGHE (Ligelizumab) Recombinant Monoclonal Antibody

Datasheet

Code	CSB-RA16849MA1HU
Size	US$210
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Image	The Binding Activity of Human IGHE with Anti-IGHE Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IGHE (CSB-MP1684HU3d7) at 2 μg/mL can bind Anti-IGHE recombinant antibody. The EC₅₀ is 3.097-4.487 ng/mL.
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Product Details
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Target Background

Product Details

Uniprot No.

P01854

Target Names

IGHE

Alternative Names

Immunoglobulin heavy constant epsilon (Ig epsilon chain C region) (Ig epsilon chain C region ND), IGHE

Species Reactivity

Human

Immunogen

Recombinant Human IGHE protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Monoclonal

Isotype

hIgG1

Clone No.

11D7

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Recommended Dilution

Application	Recommended Dilution
ELISA	1:5000-1:50000

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

Subcellular Location

Secreted. Cell membrane.

Database Links

HGNC: 5522

OMIM: 147180

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