sens Antibody

1. Using multigenerational selection experiments, study finds that for the Drosophila proneural network, the effect of genomic diversity is dampened by miR-9a-mediated regulation of senseless expression. PMID: 24360277
2. propose that SUMOylation of Senseless via lysine 509 promotes its synergy with proneural proteins during transcriptional activation and hence regulates an important step in neurogenesis leading to the formation and maturation of the sense organ precursors PMID: 22586269
3. Data found that expression of Wg target gene senseless (sens) was elevated in the sulf1 mutant wing discs. Sulf1 also negatively regulate extracellular levels of Wg. PMID: 21305649
4. Data show that in the salivary glands, senseless acts as an anti-apoptotic protein by repressing reaper and possibly hid. PMID: 12925597
5. acts as a binary switch that is fundamental to sensory organ precursor selection PMID: 14665671
6. senseless is the primary target of achaete and scute during interommatidial bristle development PMID: 15083519
7. These results indicate that the Atx-1/sensless interaction contributes to the selective Purkinje cell degeneration in SCA1. PMID: 16122429
8. Sens confers neuronal identity to epithelial cells in the wing margin. PMID: 16554363
9. Specificity of Atonal and Scute bHLH factors: analysis of cognate E box binding sites and the influence of sens are reported. PMID: 18681894
10. Hox-Senseless antagonism forms a molecular switch that integrates neural and anterior-posterior positional information. PMID: 18694568

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KEGG: dme:Dmel_CG32120

STRING: 7227.FBpp0075596

UniGene: Dm.1457