Recombinant Human Protein NOV homolog protein(NOV) (Active)

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Code CSB-AP002511HU
Product Type Growth Factor
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P48745
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered PBS, pH 7.0 ,lyophilized
Alias NovH, Insulin-like growth factor-binding protein 9, IBP-9, IGF-binding protein 9, IGFBP-9
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1.0 μg/ml, corresponding to a specific activity of >1000 IU/mg.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+QVAATQRCP PQCPGRCPAT PPTCAPGVRA VLDGCSCCLV CARQRGESCS DLEPCDESSG LYCDRSADPS NQTGICTAVE GDNCVFDGVI YRSGEKFQPS CKFQCTCRDG QIGCVPRCQL DVLLPEPNCP APRKVEVPGE CCEKWICGPD EEDSLGGLTL AAYRPEATLG VEVSDSSVNC IEQTTEWTAC SKSCGMGFST RVTNRNRQCE MLKQTRLCMV RPCEQEPEQP TDKKGKKCLR TKKSLKAIHL QFKNCTSLHT YKPRFCGVCS DGRCCTPHNT KTIQAEFQCS PGQIVKKPVM VIGTCTCHTN CPKNNEAFLQ ELELKTTRGK M
Research Area Immunology
Source E.coli
Gene Names NOV
Expression Region 28-357aa
Tag Info Tag-Free
Mol. Weight 36.2 kDa
Protein Description Full Length of Mature Protein
PubMed ID 7520150; 8622864; 14702039; 15489334; 1756408; 15340161; 9927660
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Function Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival
Subcellular Location Secreted, Cytoplasm, Cell junction, gap junction
Protein Families CCN family
Tissue Specificity Expressed in endiothelial cells (at protein level) (PubMed:21063504). Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type.
Database Links

HGNC: 7885

OMIM: 164958

KEGG: hsa:4856

STRING: 9606.ENSP00000259526

UniGene: Hs.235935

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