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| Code | CSB-E13492m |
| Size | 96T,5×96T,10×96T |
| Price | Request a Quote or Start an on-line Chat |
| Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
The mouse hepatocyte growth factor receptor (HGFR) ELISA kit is suitable for quantitatively determining mouse HGFR in serum, plasma, or tissue homogenates. This assay employs the bi-antibody sandwich technique and enzyme-substrate chromogenic reaction to quantify mouse HGFR levels in the sample. The amount of synthesized colored product is positively related to the analyte of interest in the sample.
HGFR, also called MET/c-MET, is stimulated upon HGF binding and further activates downstream effector molecules, thus eliciting Grb2-Ras-Raf-Erk/MAPK, Gab1-Shp2-Erk/MAPK, PI3K-AKT, and STAT3 signaling pathway. HGF/c-MET signaling is involved in different processes including normal development, organ regeneration, cell cycle progression, cell proliferation, survival, migration, invasion, and tumorigenesis. Dysregulation of HGF/cMET signaling plays a crucial role in several human cancers, especially in invasion and metastasis.
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STRING: 10090.ENSMUSP00000079324
UniGene: Mm.86844
