P Antibody, FITC conjugated

Code CSB-PA324598LC01HDO
Size US$166
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Product Details

Full Product Name
Rabbit anti-Hepatitis B virus genotype A2 subtype adw2 (isolate Germany/991/1990) (HBV-A) P Polyclonal antibody
Uniprot No.
Target Names
P
Alternative Names
PProtein P [Includes: DNA-directed DNA polymerase antibody; EC 2.7.7.7); RNA-directed DNA polymerase antibody; EC 2.7.7.49); Ribonuclease H antibody; EC 3.1.26.4)] antibody
Raised in
Rabbit
Species Reactivity
Hepatitis B virus genotype A2 subtype adw2
Immunogen
Recombinant Hepatitis B virus genotype A2 subtype adw2 Protein P protein (349-692AA)
Immunogen Species
Hepatitis B virus genotype A2 subtype adw2 (isolate Germany/991/1990) (HBV-A)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
Protein Families
Hepadnaviridae P protein family
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