Recombinant Borna disease virus Envelope glycoprotein p57(G),partial

Code CSB-CF345219BIN
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P52638
Relevance Unprocessed envelope protein p57 is thought to be involved in attachment of the virus to its cell surface receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Envelope protein p27 and p29 presumably linked by disulfide bond are the viral type II fusion protein, involved in pH-dependent fusion within early endosomes after internalization of the virion by endocytosis.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Species Borna disease virus (strain V) (BDV)
Purity Greater than 85% as determined by SDS-PAGE.
Sequence FDLQGLSCNTDSTPGLIDLEIRRLCHTPTENVISCEVSYLNHTTISLPAVHTSCLKYHCKTYWGFFGSYSADRIINRYTGTVKGCLNNSAPEDPFECNWFYCCSAITTEICRCSITNVTVAVQTFPPFMYCSFADCSTVSQQELESGKAMLSDGSTLTYTPYILQSEVVNKTLNGTILCNSSSKIVSFDEFRRSYSLTNGSYQSSSINVTCANYTSSCRPRLKRRRRDTQQIEYLVHKLRPTLKDAWEDCEILQSLLLGVFGTGIASASQFLRSWLNHPDIIGYIVNGVGVVWQCHRVNVTFMAWNESTYYPPVDYNGRKYFLNDEGRLQTNTPEARPGLKRVMWFGRYFLGTVGSGVKPRRIRYNKTSHDYHLEEFEASLNMTPQTSIASGHETDPINHAYGTQADLLPYTRSSNITSTDTGSGWVHIGLPSFAFLNPLGWLRD
Research Area Others
Source in vitro E.coli expression system
Gene Names G
Protein Names gp84 gp94
Expression Region 23-467aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 54.2 kDa
Protein Description Extracellular Domain
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Unprocessed envelope protein p57 is thought to be involved in attachment of the virus to its cell surface receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity).
Subcellular Location Envelope glycoprotein p57: Host endoplasmic reticulum membrane, Single-pass type I membrane protein, Note=Accumulates in the endoplasmic reticulum when unprocessed, whereas cleaved products reaches cell surface, SUBCELLULAR LOCATION: Envelope glycoprotein p27: Virion, Host cell membrane, Peripheral membrane protein, Note=Appear to be associated with infectious virions, SUBCELLULAR LOCATION: Envelope glycoprotein p29: Virion, Host cell membrane, Single-pass type I membrane protein
Database Links

KEGG: vg:26799166

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